Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25885626 | 0.89 | DGAT1 (0.34) | HDAC6LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL30989634 | 0.89 | DGAT1 (0.34) | HDAC6LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL19664191 | 0.84 | CNR2 (0.33) | HDAC6CNR2 | |
| SCHEMBL20607635 | 0.81 | DDR1 (0.35) | LMNACNR2 | |
| SCHEMBL30970975 | 0.81 | POLB (0.32) | — | |
| SCHEMBL17986662 | 0.81 | POLB (0.32) | — | |
| SCHEMBL17231835 | 0.81 | PTGS2 (0.36) | KMT2A | |
| SCHEMBL15858547 | 0.80 | LMNA (0.33) | LMNAHTTSMN1; SMN2KMT2ACNR2 | |
| SCHEMBL29431630 | 0.80 | LMNA (0.33) | LMNAHTTSMN1; SMN2KMT2ACNR2 | |
| SCHEMBL29431583 | 0.79 | DDR1 (0.36) | LMNAHTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266552-B2 | Condensed heterocyclic compound having cycloalkylpyridyl group or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | NIHON NOHYAKU CO., LTD. (JP) | 2019-04-23 | — | — | US | disclosed |
| WO-2016121997-A1 | FUSED HETEROCYCLIC COMPOUND HAVING CYCLOALKYLPYRIDYL GROUP OR SALT THEREOF, AND AGRICULTURAL OR HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND AND USE METHOD THEREFOR | 日本農薬株式会社 | 2016-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266552-B2 | Condensed heterocyclic compound having cycloalkylpyridyl group or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | DDT, HCN3, HCN1 | HDAC6 505/4885LMNA 1424/4885GAA 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.