Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | S100B | P04271 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17987795 | 0.82 | NPY4R (0.41) | ALDH1A1 | |
| SCHEMBL17987791 | 0.82 | NPY4R (0.41) | ALDH1A1 | |
| SCHEMBL20687494 | 0.82 | ALDH1A1 (0.37) | ALDH1A1F10MTNR1AMTNR1BKDM4E | |
| SCHEMBL16521943 | 0.80 | F10 (0.41) | PRSS1TMPRSS2F2PRMT1ST14 | |
| SCHEMBL16218949 | 0.80 | PRSS1 (0.46) | PRSS1ALDH1A1TMPRSS2F2PRMT1 | |
| SCHEMBL17058979 | 0.80 | DRD2 (0.49) | PRSS1ALDH1A1TMPRSS2F2PRMT1 | |
| SCHEMBL304917 | 0.80 | PRSS1 (0.46) | PRSS1TMPRSS2F2PRMT1ST14 | |
| SCHEMBL10310260 | 0.80 | MTNR1A (0.63) | PRSS1ALDH1A1DRD3MTNR1AMTNR1B | |
| SCHEMBL10310294 | 0.80 | MTNR1A (0.59) | PRSS1ALDH1A1F2F10PLG | |
| SCHEMBL17960697 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MTNR1AMTNR1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172885-A1 | THIOL-CONTAINING COMPOUNDS FOR USE IN TREATING CORONAVIRUS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-06-08 | — | — | US | disclosed |
| US-10968233-B2 | Monothiol mucolytic agents | PARION SCIENCES, INC. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20190031679-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. | 2019-01-31 | — | — | US | disclosed |
| US-20160222023-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172885-A1 | THIOL-CONTAINING COMPOUNDS FOR USE IN TREATING CORONAVIRUS | CTH, SARS1, CBS | PRSS1 240/4885ALDH1A1 552/4885TMPRSS2 21/4885 |
| US-10968233-B2 | Monothiol mucolytic agents | MUC1, HRH2, MAN2A1 | PRSS1 142/4885ALDH1A1 301/4885TMPRSS2 366/4885 |
| US-20190031679-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | MUC1, MAN2A1, HRH2 | PRSS1 101/4885ALDH1A1 266/4885TMPRSS2 262/4885 |
| US-20160222023-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | MUC1, MAN2A1, HRH2 | PRSS1 101/4885ALDH1A1 266/4885TMPRSS2 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.