SCHEMBL17988076

SCHEMBL17988076

Cc1nc2cc(C(F)(F)F)c(-c3cc4oc(C)nc4cc3C(F)(F)F)cc2o1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LRRK2 Q5S007 1/20 0.45
CHRNB2 P17787 1/20 0.44
CHRNA4 P43681 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.41
GAA P10253 2/20 0.41
ALDH1A1 P00352 2/20 0.39
POLB P06746 2/20 0.36
RAB9A P51151 3/20 0.35
NPC1 O15118 2/20 0.35
STAT1 P42224 1/20 0.35
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
DRD3 P35462 1/20 0.32
KCNH2 Q12809 1/20 0.32
LMNA P02545 1/20 0.32
ESR2 Q92731 1/20 0.32
ELANE P08246 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19914259 0.87 LRRK2 (0.44) LRRK2CHRNB2CHRNA4SMN1; SMN2L3MBTL1
SCHEMBL19914257 0.81 LRRK2 (0.51) LRRK2CHRNB2CHRNA4SMN1; SMN2L3MBTL1
SCHEMBL17988060 0.79 LMNA (0.46) LRRK2POLBKDM4ELMNAESR2
SCHEMBL2756560 0.77 L3MBTL1 (0.53) LRRK2CHRNB2CHRNA4SMN1; SMN2L3MBTL1
SCHEMBL24910475 0.77 L3MBTL1 (0.43) LRRK2CHRNB2CHRNA4SMN1; SMN2L3MBTL1
SCHEMBL3180303 0.76 GAA (0.46) LRRK2CHRNB2CHRNA4SMN1; SMN2L3MBTL1
SCHEMBL9912823 0.75 L3MBTL1 (0.52) LRRK2CHRNB2CHRNA4SMN1; SMN2L3MBTL1
SCHEMBL19914273 0.74 ALDH1A1 (0.56) CHRNB2CHRNA4SMN1; SMN2L3MBTL1GAA
SCHEMBL12021909 0.74 CHRNB2 (0.44) LRRK2CHRNB2CHRNA4SMN1; SMN2L3MBTL1
SCHEMBL8257950 0.73 GAA (0.43) LRRK2CHRNB2CHRNA4SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11333976-B2 Resin, photosensitive resin composition, electronic component and display device using the same TORAY INDUSTRIES, INC. (JP) 2022-05-17 US disclosed
US-20180011402-A1 RESIN, PHOTOSENSITIVE RESIN COMPOSITION, ELECTRONIC COMPONENT AND DISPLAY DEVICE USING THE SAME TORAY INDUSTRIES, INC. (JP) 2018-01-11 US disclosed
WO-2016121691-A1 RESIN, PHOTOSENSITIVE RESIN COMPOSITION, AND ELECTRONIC COMPONENT AND DISPLAY DEVICE EACH USING SAME 東レ株式会社 2016-08-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180011402-A1 RESIN, PHOTOSENSITIVE RESIN COMPOSITION, ELECTRONIC COMPONENT AND DISPLAY DEVICE USING THE SAME EED, RPL19, RARA LRRK2 3692/4885CHRNB2 3547/4885CHRNA4 3200/4885
US-11333976-B2 Resin, photosensitive resin composition, electronic component and display device using the same EED, RPL19, RARA LRRK2 3692/4885CHRNB2 3547/4885CHRNA4 3200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.