Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17991993 | 0.88 | LMNA (0.45) | LMNANPC1MAPTRAB9AKDM4E | |
| SCHEMBL17991991 | 0.87 | LMNA (0.49) | LMNASTS | |
| SCHEMBL17991992 | 0.83 | LMNA (0.49) | LMNANPC1MAPTRAB9AKDM4E | |
| SCHEMBL17988722 | 0.81 | ALDH1A1 (0.35) | ALDH1A1CYP1A2GLAGAA | |
| SCHEMBL17992004 | 0.81 | LMNA (0.54) | LMNANPC1MAPTRAB9AKDM4E | |
| SCHEMBL17991985 | 0.80 | LMNA (0.45) | LMNANPC1MAPTRAB9AKDM4E | |
| SCHEMBL17988686 | 0.80 | MAPT (0.50) | LMNANPC1MAPTRAB9AKDM4E | |
| SCHEMBL14699614 | 0.80 | MAPT (0.50) | LMNANPC1MAPTRAB9AKDM4E | |
| SCHEMBL17991987 | 0.74 | MAPT (0.43) | LMNANPC1MAPTRAB9AKDM4E | |
| SCHEMBL17988693 | 0.71 | PTGS2 (0.44) | LMNANPC1MAPTRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409859-B2 | Substituted diphenyl derivatives | CREATIVE THERAPEUTICS GMBH (DE) | 2016-08-09 | — | — | US | disclosed |