Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 19/20 | 0.41 |
| ▸ | HPGD | P15428 | 18/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 17/20 | 0.41 |
| ▸ | GAA | P10253 | 15/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.41 |
| ▸ | GLA | P06280 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 12/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18005349 | 0.78 | KDM4E (0.41) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL18005325 | 0.78 | NPC1 (0.40) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL18005276 | 0.78 | PRCP (0.42) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL18005487 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL18005326 | 0.77 | CETP (0.36) | ALDH1A1HPGDKDM4EHSD17B10CYP1A2 | |
| SCHEMBL18005566 | 0.77 | ALOX15 (0.43) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL16399641 | 0.77 | GRM5 (0.43) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL18005356 | 0.77 | L3MBTL1 (0.40) | KDM4EGAANPC1RAB9AL3MBTL1 | |
| SCHEMBL18005215 | 0.76 | NOTUM (0.36) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL1249333 | 0.75 | ADORA2A (0.41) | ALDH1A1HPGDKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | ALDH1A1 1611/4885HPGD 2152/4885KDM4E 2681/4885 |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | ALDH1A1 1611/4885HPGD 2152/4885KDM4E 2681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.