Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 15/20 | 0.70 |
| ▸ | HTR1A | P08908 | 13/20 | 0.70 |
| ▸ | HTR1D | P28221 | 4/20 | 0.70 |
| ▸ | HTR1B | P28222 | 4/20 | 0.70 |
| ▸ | HTR2A | P28223 | 4/20 | 0.70 |
| ▸ | HTR2C | P28335 | 4/20 | 0.70 |
| ▸ | HTR2B | P41595 | 4/20 | 0.70 |
| ▸ | HTR5A | P47898 | 2/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.69 |
| ▸ | DRD2 | P14416 | 1/20 | 0.67 |
| ▸ | DRD3 | P35462 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18028066 | 0.99 | HTR7 (0.71) | HTR7HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL18010380 | 0.99 | HTR7 (0.71) | HTR7HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL18010351 | 0.99 | HTR7 (0.71) | HTR7HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL18010356 | 0.97 | DRD2 (0.67) | HTR7HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL7300518 | 0.85 | HTR7 (0.77) | HTR7HTR1AHTR2ADRD2DRD3 | |
| SCHEMBL6526368 | 0.85 | DRD2 (0.85) | HTR7HTR1AHTR2ADRD2DRD3 | |
| SCHEMBL18896514 | 0.84 | HTR7 (0.54) | HTR7HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL18010431 | 0.83 | HTR7 (1.00) | HTR7HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL13875119 | 0.82 | HTR1A (1.00) | HTR7HTR1ADRD2DRD3 | |
| SCHEMBL25703545 | 0.82 | HTR7 (0.58) | HTR7HTR1AHTR1DHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-08-25 | — | — | US | claimed |
| WO-2023120963-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING LUNG CANCER COMPRISING CARBAZOLE DERIVATIVE COMPOUND AS ACTIVE INGREDIENT | 한국과학기술연구원 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023120963-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING LUNG CANCER COMPRISING CARBAZOLE DERIVATIVE COMPOUND AS ACTIVE INGREDIENT | 한국과학기술연구원 | 2023-06-29 | — | — | WO | disclosed |
| US-9663464-B2 | Carbazole derivatives acting on 5-HT7 receptor | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-05-30 | — | — | US | disclosed |
| US-9663464-B2 | Carbazole derivatives acting on 5-HT7 receptor | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-05-30 | — | — | US | disclosed |
| US-9663464-B2 | Carbazole derivatives acting on 5-HT7 receptor | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-05-30 | — | — | US | disclosed |
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-08-25 | — | — | US | disclosed |
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-08-25 | — | — | US | disclosed |
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | HTR7, HTR3A, HTR3B | HTR7 1/4885HTR1A 4/4885HTR1D 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.