SCHEMBL1801303

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1802810	0.89	POLB (0.38)	ROCK2POLBALDH1A1KDM4EMEN1
	SCHEMBL1800927	0.88	ROCK2 (0.40)	ROCK2POLBALDH1A1MEN1KMT2A
	SCHEMBL1801238	0.88	POLB (0.41)	ROCK2POLBALDH1A1MEN1KMT2A
	SCHEMBL1800564	0.85	POLB (0.42)	ROCK2POLBALDH1A1MEN1KMT2A
	SCHEMBL1802453	0.81	ALDH1A1 (0.39)	ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2
	SCHEMBL1803218	0.81	ALDH1A1 (0.55)	ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2
	SCHEMBL1801453	0.80	MEN1 (0.37)	ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2
	SCHEMBL1802615	0.80	ALDH1A1 (0.41)	ALDH1A1KDM4EMEN1KMT2ARAB9A
	SCHEMBL1802738	0.79	ALDH1A1 (0.43)	POLBALDH1A1KDM4EMEN1KMT2A
	SCHEMBL1800359	0.79	SIGMAR1 (0.41)	POLBALDH1A1KDM4ESMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.