Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 6/20 | 0.36 |
| ▸ | ALDH1A2 | O94788 | 3/20 | 0.36 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19933706 | 0.94 | ALDH1A3 (0.39) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL20068728 | 0.91 | ALDH1A1 (0.38) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL21125818 | 0.89 | ALDH1A1 (0.40) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL19933621 | 0.88 | RAB9A (0.39) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL21398027 | 0.87 | TGFBR1 (0.34) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL19933697 | 0.87 | KMT2A (0.38) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL19933828 | 0.86 | LPL (0.39) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL23956274 | 0.85 | ALDH1A3 (0.39) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL23956355 | 0.85 | ALDH1A1 (0.36) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL23956235 | 0.83 | TGFBR1 (0.34) | ALDH1A1RAB9ANPC1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| WO-2016124304-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | ALDH1A1 2742/4885RAB9A 2171/4885NPC1 4039/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | ALDH1A1 2597/4885RAB9A 1433/4885NPC1 2761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.