SCHEMBL180153

SCHEMBL180153

NC(Cc1ccc(O)c(C(=O)O)c1)C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 4/20 0.73
▸ KDM4E B2RXH2 4/20 0.73
▸ HSD17B10 Q99714 4/20 0.73
▸ TDP1 Q9NUW8 4/20 0.73
▸ LCK P06239 3/20 0.73
▸ USP2 O75604 3/20 0.73
▸ PTGS1 P23219 2/20 0.73
▸ EGFR P00533 2/20 0.73
▸ ALOX15 P16050 2/20 0.73
▸ RECQL P46063 2/20 0.73
▸ HIF1A Q16665 2/20 0.73
▸ FYN P06241 1/20 0.73
▸ ADORA3 P0DMS8 1/20 0.73
▸ HTR2A P28223 1/20 0.73
▸ PTGS2 P35354 1/20 0.73
▸ KLKB1 P03952 1/20 0.61
▸ CTSB P07858 1/20 0.61
▸ MMP9 P14780 1/20 0.61
▸ DNMT1 P26358 1/20 0.61
▸ DNMT3B Q9UBC3 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30863848 1.00 SLC7A5 (0.73) SLC7A5KDM4EHSD17B10TDP1LCK
SCHEMBL30863849 1.00 SLC7A5 (0.73) SLC7A5KDM4EHSD17B10TDP1LCK
SCHEMBL28840880 1.00 SLC7A5 (0.73) SLC7A5KDM4EHSD17B10TDP1LCK
SCHEMBL180154 1.00 SLC7A5 (0.73) SLC7A5KDM4EHSD17B10TDP1LCK
SCHEMBL25357608 0.89 SLC7A5 (0.71) SLC7A5KDM4EHSD17B10TDP1LCK
SCHEMBL2558965 0.89 SLC7A5 (0.71) SLC7A5KDM4EHSD17B10TDP1LCK
SCHEMBL30665436 0.89 SLC7A5 (0.71) SLC7A5KDM4EHSD17B10TDP1LCK
SCHEMBL2558959 0.89 SLC7A5 (0.71) SLC7A5KDM4EHSD17B10TDP1LCK
SCHEMBL25357600 0.89 SLC7A5 (0.71) SLC7A5KDM4EHSD17B10TDP1LCK
SCHEMBL2554990 0.89 SLC7A5 (0.71) SLC7A5KDM4EHSD17B10TDP1LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843513-B Preparation method of (S) -3-Carboxytyrosine 深圳创元生物医药科技有限公司 2024-05-28 — — CN claimed
CN-117843513-A Preparation method of (S) -3-Carboxytyrosine 深圳创元生物医药科技有限公司 2024-04-09 — — CN claimed
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2023-08-17 — — US claimed
US-9101662-B2 Compositions with modulating agents FOAMIX PHARMACEUTICALS LTD. (IL) 2015-08-11 — — US claimed
US-8795693-B2 Compositions with modulating agents FOAMIX LTD. (IL) 2014-08-05 — — US claimed
EP-2097065-A2 FOAMABLE WATERLESS COMPOSITIONS WITH MODULATING AGENTS Foamix Ltd. (IL) 2009-09-09 — — EP claimed
WO-2008152444-A2 FOAMABLE WATERLESS COMPOSITIONS WITH MODULATING AGENTS FOAMIX LTD. (US) 2008-12-18 — — WO claimed
US-20080206159-A1 Drug mixture contains solvents, nonionic surfactants, gelling agent, therapeutic active agent, liquefied or compressed gas propellant; pressurized dispenser; treating skin diseases, dermal and mucosal delivery; stable and non-irritating emulsions FOAMIX LTD. (IL) 2008-08-28 — — US claimed
US-7176185-B2 Short peptide carrier system for cellular delivery of agent TSRL, INC. (US) 2007-02-13 — — US claimed
US-7053214-B2 β-sheet mimetics and composition and methods relating thereto MYRIAD GENETICS, INC. (US) 2006-05-30 — — US claimed
US-20050208140-A1 Short peptide carrier system for cellular delivery of agent TSRL, INC. 2005-09-22 — — US claimed
US-6943157-B2 Reverse-turn mimetics and composition and methods relating thereto MYRIAD GENETICS, INC. (US) 2005-09-13 — — US claimed
WO-2004021981-A2 METHODS FOR THE PREPARATION OF β-AMINO ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2004-03-18 — — WO claimed
US-20030113882-A1 Methods for the preparation of beta-amino acids WISCONSIN ALUMNI RESEARCH FOUNDATION 2003-06-19 — — US claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 — — US claimed
EP-0482966-A2 Stabilised derivatives of fragments of hirudin, their preparation and pharmaceutical preparations ADIR ET COMPAGNIE (FR) 1992-04-29 — — EP claimed
US-20250361274-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT PEPTIDREAM INC. (JP) 2025-11-27 — — US disclosed
EP-4541805-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT PeptiDream Inc. (JP) 2025-04-23 — — EP disclosed
EP-0308983-A2 NMR imaging with Mn(II) coordination compositions SALUTAR, INC. (US) 1989-03-29 — — EP disclosed
US-4627915-A SURFACE CONTAINING HYDROPHOBIC MEMBER AND NEGATIVE CHARGE PRODUCING MEMBER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1986-12-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050208140-A1 Short peptide carrier system for cellular delivery of agent SLC43A1, DNPEP, LNPEP SLC7A5 6/4885KDM4E 4849/4885HSD17B10 4705/4885
US-20080206159-A1 Drug mixture contains solvents, nonionic surfactants, gelling agent, therapeutic active agent, liquefied or compressed gas propellant; pressurized dispenser; treating skin diseases, dermal and mucosal delivery; stable and non-irritating emulsions CUTA, SLTM, SMO SLC7A5 4410/4885KDM4E 4432/4885HSD17B10 2443/4885
US-20250361274-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT BMP4, BMP1, BMPR2 SLC7A5 2541/4885KDM4E 1440/4885HSD17B10 4643/4885
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP SLC7A5 21/4885KDM4E 4463/4885HSD17B10 3966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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