SCHEMBL1802188

SCHEMBL1802188

CCC(C)c1cccc(N)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC8 Q9BY41 1/20 0.53
ALDH1A1 P00352 2/20 0.52
USP2 O75604 1/20 0.52
GAA P10253 1/20 0.52
PKM P14618 1/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CYP3A4 P08684 6/20 0.44
CASP1 P29466 1/20 0.44
RECQL P46063 1/20 0.44
CPN1 P15169 1/20 0.43
CPB2 Q96IY4 1/20 0.43
TP53 P04637 1/20 0.42
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
TAAR1 Q96RJ0 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13256250 1.00 HDAC4 (0.53) HDAC4HDAC2HDAC8ALDH1A1USP2
SCHEMBL1006801 0.84 HDAC4 (0.62) HDAC4HDAC2HDAC8ALDH1A1USP2
SCHEMBL14465479 0.84 CPN1 (0.41) HDAC4HDAC2HDAC8ALDH1A1USP2
SCHEMBL9255104 0.84 CPN1 (0.41) HDAC4HDAC2HDAC8ALDH1A1USP2
SCHEMBL8685825 0.82 CPN1 (0.46) HDAC4HDAC2HDAC8ALDH1A1USP2
SCHEMBL21092205 0.82 CYP3A4 (0.42) ALDH1A1CYP3A4CASP1RECQLCPN1
SCHEMBL21124173 0.81 TSHR (0.44) HDAC4HDAC2HDAC8ALDH1A1USP2
SCHEMBL9402905 0.81 CPN1 (0.49) ALDH1A1CYP3A4CASP1RECQLCPN1
SCHEMBL20032392 0.81 CYP3A4 (0.46) ALDH1A1CYP3A4CASP1RECQLCPN1
SCHEMBL1100916 0.80 ESR1 (0.46) ALDH1A1CYP3A4CASP1RECQLCPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731689-A1 METHOD FOR THE PRODUCTION OF THERMOPLASTIC POLYOXAZOLIDINONE Covestro Deutschland AG (DE) 2026-04-29 EP disclosed
US-12528792-B2 Sulfonamide compounds and the use thereof in the treatment of cancer TroBio Therapeutics Pty Ltd (AU) 2026-01-20 US disclosed
EP-4200352-B1 METHOD FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE COVESTRO DEUTSCHLAND AG (DE) 2025-11-19 EP disclosed
EP-4200353-B1 METHOD FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE COVESTRO DEUTSCHLAND AG (DE) 2025-11-19 EP disclosed
EP-4200351-B1 METHOD FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE COVESTRO DEUTSCHLAND AG (DE) 2025-11-19 EP disclosed
EP-4448605-B1 PROCESS FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE COVESTRO DEUTSCHLAND AG (DE) 2025-11-19 EP disclosed
US-12466913-B2 Method for the production of a thermoplastic polyoxazolidinone COVESTRO DEUTSCHLAND AG (DE) 2025-11-11 US disclosed
US-12378348-B2 Method for the production of a thermoplastic polyoxazolidinone COVESTRO DEUTSCHLAND AG (DE) 2025-08-05 US disclosed
US-20250043061-A1 PROCESS FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE COVESTRO DEUTSCHLAND AG (DE) 2025-02-06 US disclosed
WO-2024260858-A1 METHOD FOR THE PRODUCTION OF THERMOPLASTIC POLYOXAZOLIDINONE COVESTRO DEUTSCHLAND AG (DE) 2024-12-26 WO disclosed
US-9669046-B2 Biodefenses using triazole-containing macrolides CEMPRA PHARMACEUTICALS, INC. (US) 2017-06-06 US disclosed
US-20170095476-A1 SPIROCYCLIC COMPOUNDS AS TRYPTOPHAN HYDROXYLASE INHIBITORS ALTAVANT SCIENCES GMBH (CH) 2017-04-06 US disclosed
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed
WO-2009125606-A1 PAI-1 INHIBITOR 株式会社医薬分子設計研究所 (JP) 2009-10-15 WO disclosed
EP-1966265-A2 BLENDS OF DIAMINES HAVING REDUCED COLOR Albermarle Corporation (US) 2008-09-10 EP disclosed
WO-2007079365-A2 BLENDS OF DIAMINES HAVING REDUCED COLOR ALBEMARLE CORPORATION (US) 2007-07-12 WO disclosed
EP-0023718-B1 PROCESS FOR THE TRANSFER PRINTING OF SYNTHETIC, HYDROPHOBIC FIBROUS MATERIAL CASSELLA Aktiengesellschaft (DE) 1983-03-23 EP disclosed
US-4306874-A Process for printing synthetic, hydrophobic fiber material in accordance with the principle of transfer printing CASSELLA AKTIENGESELLSCHAFT (DE) 1981-12-22 US disclosed
EP-0023718-A1 Process for the transfer printing of synthetic, hydrophobic fibrous material CASSELLA Aktiengesellschaft (DE) 1981-02-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170095476-A1 SPIROCYCLIC COMPOUNDS AS TRYPTOPHAN HYDROXYLASE INHIBITORS TPH1, TPH2, HTR1A HDAC4 701/4885HDAC2 576/4885HDAC8 1335/4885
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 HDAC4 4081/4885HDAC2 3557/4885HDAC8 4379/4885
US-12528792-B2 Sulfonamide compounds and the use thereof in the treatment of cancer SLC10A6, SLCO4C1, SLCO2A1 HDAC4 837/4885HDAC2 741/4885HDAC8 796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.