Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 13/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16330798 | 0.87 | S1PR3 (0.52) | S1PR3S1PR1S1PR2 | |
| SCHEMBL12437132 | 0.87 | S1PR3 (0.40) | S1PR3CYP1A2CYP2D6CYP2C19RAB9A | |
| SCHEMBL12438374 | 0.86 | S1PR3 (0.39) | HDAC1HDAC8HDAC6S1PR3CYP1A2 | |
| SCHEMBL12437133 | 0.85 | TAS1R3 (0.40) | HDAC1HDAC8HDAC6S1PR3CYP1A2 | |
| SCHEMBL14120380 | 0.85 | TRPV1 (0.46) | HDAC1HDAC8HDAC6S1PR3RAB9A | |
| SCHEMBL12437616 | 0.85 | ALDH1A1 (0.46) | S1PR3RAB9AS1PR1MEN1KMT2A | |
| SCHEMBL12437620 | 0.84 | MEN1 (0.46) | HDAC1HDAC8HDAC6S1PR3CYP1A2 | |
| SCHEMBL12437547 | 0.83 | S1PR3 (0.43) | S1PR3S1PR1ARMEN1KMT2A | |
| SCHEMBL14120559 | 0.83 | LMNA (0.48) | S1PR3S1PR1MEN1KMT2A | |
| SCHEMBL9894400 | 0.75 | S1PR3 (0.47) | S1PR3S1PR1ARS1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531484-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-17 | — | — | EP | disclosed |