Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 12/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14120380 | 0.87 | TRPV1 (0.46) | S1PR3S1PR1RAB9ANPC1HDAC1 | |
| SCHEMBL12437133 | 0.87 | TAS1R3 (0.40) | S1PR3S1PR1RAB9AHDAC1HDAC8 | |
| SCHEMBL18023968 | 0.86 | HDAC1 (0.42) | S1PR3S1PR1RAB9AHDAC1HDAC8 | |
| SCHEMBL14121227 | 0.84 | PNLIP (0.38) | S1PR3S1PR1RAB9ANPC1KCNQ3 | |
| SCHEMBL12437616 | 0.83 | ALDH1A1 (0.46) | S1PR3S1PR1RAB9ANPC1MEN1 | |
| SCHEMBL12437620 | 0.82 | MEN1 (0.46) | S1PR3S1PR1HDAC1HDAC8HDAC6 | |
| SCHEMBL12437132 | 0.81 | S1PR3 (0.40) | S1PR3S1PR1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL16330798 | 0.81 | S1PR3 (0.52) | S1PR3S1PR1 | |
| SCHEMBL14120559 | 0.78 | LMNA (0.48) | S1PR3S1PR1MEN1KMT2A | |
| SCHEMBL12437547 | 0.78 | S1PR3 (0.43) | S1PR3S1PR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531484-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-17 | — | — | EP | disclosed |
| US-20120309812-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-06 | — | — | US | disclosed |
| WO-2011095462-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309812-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, NISCH | S1PR3 1546/4885S1PR1 2246/4885RAB9A 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.