Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | FABP6 | P51161 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18029395 | 0.85 | KDM4E (0.65) | ALDH1A1KDM4EALOX15FABP6MAPK1 | |
| SCHEMBL3323252 | 0.83 | KDM4E (0.65) | ALDH1A1KDM4EALOX15FABP6MAPK1 | |
| SCHEMBL31329773 | 0.82 | FABP6 (0.67) | ALDH1A1KDM4EALOX15FABP6MAPK1 | |
| SCHEMBL28121975 | 0.82 | FABP6 (0.67) | ALDH1A1KDM4EALOX15FABP6MAPK1 | |
| SCHEMBL9640623 | 0.82 | HRH2 (0.70) | ALDH1A1KDM4EALOX15FABP6MAPK1 | |
| SCHEMBL9763711 | 0.82 | PKM (0.74) | ALDH1A1KDM4EFABP6MAPK1SMN1; SMN2 | |
| SCHEMBL13152841 | 0.81 | ALDH1A1 (0.62) | ALDH1A1FABP6MAPK1TDP1PKM | |
| SCHEMBL14067207 | 0.81 | FABP6 (0.64) | ALDH1A1KDM4EALOX15FABP6MAPK1 | |
| SCHEMBL31329800 | 0.81 | MAPK1 (0.69) | ALDH1A1KDM4EALOX15FABP6MAPK1 | |
| SCHEMBL12225719 | 0.81 | MAPK1 (0.69) | ALDH1A1KDM4EALOX15FABP6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244435-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244435-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | NQO1, TXN2, MPO | ALDH1A1 1589/4885KDM4E 3910/4885ALOX15 1407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.