SCHEMBL1803452

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1800729	0.85	CYP2D6 (0.50)	NPC1CYP2D6CYP2C9CYP1A2TSHR
	SCHEMBL2941350	0.85	CYP2D6 (0.50)	CYP2D6CYP2C9CYP1A2TSHRCYP2C19
	SCHEMBL1802019	0.83	MGLL (0.39)	CYP2D6CYP2C9CYP3A4USP2
	SCHEMBL1800844	0.83	HTT (0.39)	ALDH1A1SMN1; SMN2LMNA
	SCHEMBL1803334	0.82	LMNA (0.42)	NPC1RAB9AKMT2AMEN1TSHR
	SCHEMBL3006559	0.82	CCR5 (0.35)	NPC1RAB9AKMT2AMEN1ALDH1A1
	SCHEMBL2940036	0.82	CCR5 (0.38)	NPC1RAB9AKMT2AMEN1CYP2C9
	SCHEMBL1801647	0.81	RAB9A (0.41)	RAB9AKMT2AMEN1SMN1; SMN2
	SCHEMBL1804306	0.81	HPGD (0.43)	NPC1RAB9AKMT2AMEN1CYP2D6
	SCHEMBL1802535	0.81	HPGD (0.41)	TSHRALDH1A1SMN1; SMN2USP2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.