Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nagilactone E SCHEMBL30496589 | 0.73 | JUN (0.65) | JUNSTAT3 | |
| SCHEMBL18034508 | 0.56 | LMNA (0.33) | STAT3 | |
| SCHEMBL18034497 | 0.56 | LMNA (0.46) | — | |
| SCHEMBL17853715 | 0.55 | UBE2D3 (0.31) | — | |
| SCHEMBL18034519 | 0.54 | JUN (0.40) | JUNSTAT3 | |
| SCHEMBL11989123 | 0.54 | MGAM (0.31) | — | |
| SCHEMBL18034517 | 0.52 | JUN (0.57) | JUNSTAT3 | |
| SCHEMBL19052044 | 0.51 | PPARG (0.33) | — | |
| SCHEMBL12464454 | 0.47 | HIF1A (0.33) | — | |
| SCHEMBL1827849 | 0.46 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107405330-B | Bamboo Bai ester compound with hypolipidemic activity, and preparation method and application thereof | 中国科学院上海药物研究所 | 2023-08-01 | — | — | CN | disclosed |
| WO-2022143617-A1 | NAGILACTONE COMPOUND AND USE THEREOF IN PREPARATION OF ANTI-TUMOR DRUG | 中国科学院上海药物研究所 | 2022-07-07 | — | — | WO | disclosed |