SCHEMBL1804342

SCHEMBL1804342

Nc1[c]c2cc3ccccc3cc2cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALOX15 P16050 1/20 0.46
CASP1 P29466 1/20 0.46
CASP7 P55210 1/20 0.46
HBB P68871 1/20 0.46
HIF1A Q16665 1/20 0.46
PDPK1 O15530 1/20 0.39
HTR3A P46098 1/20 0.35
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CYP2A6 P11509 4/20 0.33
CYP1A2 P05177 3/20 0.33
GAA P10253 1/20 0.33
RCE1 Q9Y256 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5634758 0.79 ALDH1A1 (0.37) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL729534 0.79 ALDH1A1 (0.37) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL15366386 0.76 ALDH1A1 (0.40) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL195377 0.75 ALDH1A1 (0.36) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL1128294 0.74 CYP1A2 (0.43) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL1127747 0.74 CYP2A6 (0.43) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL328771 0.74 CYP2A6 (0.43) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL1128123 0.74 CYP2A6 (0.43) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL1127451 0.74 CYP2A6 (0.43) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL17707233 0.74 ALDH1A1 (0.37) ALDH1A1CYP3A4HSD17B10TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7709104-B2 Aminoanthryl derivative-substituted pyrene compound and organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2010-05-04 US claimed
US-7375250-B2 Aminoanthryl derivative substitution compound and organic electroluminescence device using the same CANON KABUSHIKI KAISHA (JP) 2008-05-20 US claimed
US-20060125378-A1 Aminoanthryl derivative substitution compound and organic electroluminescence device using the same CANON KABUSHIKI KAISHA (JP) 2006-06-15 US claimed
US-20060115678-A1 Aminoanthryl derivative-substituted pyrene compound and organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2006-06-01 US claimed
WO-2005000787-A1 AMINOANTHRYL DERIVATIVE SUBSTITUTION COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2005-01-06 WO claimed
EP-3002310-B1 COMPOSITION FOR PREPARING POLYIMIDE-INORGANIC PARTICLE COMPOSITE, POLYIMIDE-INORGANIC PARTICLE COMPOSITE, ARTICLE, AND OPTICAL DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-11-25 EP disclosed
EP-2388843-B1 Organic material and organic light emitting diode display using same SAMSUNG DISPLAY CO LTD (KR) 2019-08-07 EP disclosed
US-10153450-B2 Fused aromatic derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2018-12-11 US disclosed
US-10059805-B2 Composition for preparing polyimide-inorganic particle composite, article prepared therefrom, and optical device comprising same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-08-28 US disclosed
EP-2213641-B1 FUSED AROMATIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO (JP) 2018-05-16 EP disclosed
US-20160096927-A1 COMPOSITION FOR PREPARING POLYIMIDE-INORGANIC PARTICLE COMPOSITE, ARTICLE PREPARED THEREFROM, AND OPTICAL DEVICE COMPRISING SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-04-07 US disclosed
EP-3002310-A1 COMPOSITION FOR PREPARING POLYIMIDE-INORGANIC PARTICLE COMPOSITE, POLYIMIDE-INORGANIC PARTICLE COMPOSITE, ARTICLE, AND OPTICAL DEVICE Samsung Electronics Co., Ltd. (KR) 2016-04-06 EP disclosed
US-4197120-A ELECTRICALLY PHOTOSENSITIVE PARTICLES CONTAINING COLORANT HAVING ABSORPTION MAXIMUM GREATER THAN 410 NANOMETERS EASTMAN KODAK COMPANY (US) 1980-04-08 US disclosed
US-RE30235-E FOR ELECTROPHORETIC MIGRATION IMAGING PROCESSES EASTMAN KODAK COMPANY (US) 1980-03-18 US disclosed
US-4175961-A DISPERSION OF A POLYMER HAVING ALKYLIDENE DIARYLENE GROUPS, A PYRYLIUM-TYPE DYE SALT, AND A BIS(N,N-DISUBSTITUTED ANILINE DERIVATIVE AS A SENSITIZER EASTMAN KODAK COMPANY (US) 1979-11-27 US disclosed
US-4127412-A BIS(AMINOARYL)ALKANES EASTMAN KODAK COMPANY (US) 1978-11-28 US disclosed
US-4111693-A PYRYLIUM TYPE DYE SALT EASTMAN KODAK COMPANY (US) 1978-09-05 US disclosed
US-4092162-A Nitrogen containing polymers aelements EASTMAN KODAK COMPANY (US) 1978-05-30 US disclosed
US-4025341-A CONDENSATION POLYMER OF A TERTIARY AROMATIC AMINE, A SENSITIZER, AND A CARBONYL COMPOUND EASTMAN KODAK COMPANY (US) 1977-05-24 US disclosed
US-4012376-A Photosensitive colorant materials EASTMAN KODAK COMPANY (US) 1977-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060125378-A1 Aminoanthryl derivative substitution compound and organic electroluminescence device using the same ALAD, TYR, DDC ALDH1A1 284/4885CYP3A4 448/4885HSD17B10 2637/4885
US-10153450-B2 Fused aromatic derivative and organic electroluminescence device using the same NRAS, RSU1, RAP1A ALDH1A1 456/4885CYP3A4 3848/4885HSD17B10 4287/4885
US-20060115678-A1 Aminoanthryl derivative-substituted pyrene compound and organic light-emitting device ALAD, PAH, PPOX ALDH1A1 697/4885CYP3A4 31/4885HSD17B10 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.