Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | BMP1 | P13497 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 3/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.30 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18048546 | 1.00 | MMP2 (0.36) | MMP2MMP9MMP8BMP1MMP1 | |
| SCHEMBL25672807 | 0.80 | ALDH1A1 (0.37) | MMP1MME | |
| SCHEMBL22457640 | 0.78 | FFAR2 (0.33) | MMP1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL30408938 | 0.77 | MMP1 (0.35) | MMP9MMP1CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL22561303 | 0.77 | MMP1 (0.35) | MMP9MMP1CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL19522520 | 0.77 | MMP1 (0.35) | MMP9MMP1CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL25662649 | 0.77 | MMP1 (0.35) | MMP9MMP1CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL18048550 | 0.75 | MMP2 (0.37) | MMP2MMP9MMP8BMP1MMP1 | |
| SCHEMBL18048549 | 0.75 | MMP2 (0.37) | MMP2MMP9MMP8BMP1MMP1 | |
| SCHEMBL18272890 | 0.72 | ADAM17 (0.40) | MMP2MMP9MMP8BMP1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268038-A1 | ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO FLT3 PROTEINS | Agensys, Inc. (US) | 2018-01-17 | — | — | EP | disclosed |
| WO-2016145099-A1 | ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO FLT3 PROTEINS | AGENSYS, INC. (US) | 2016-09-15 | — | — | WO | disclosed |