Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LPO | P22079 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18054133 | 0.92 | ELANE (0.34) | NPSR1LPOLMNACYP1A2ALDH1A1 | |
| SCHEMBL18052970 | 0.89 | ALDH1A1 (0.39) | LPOLMNACYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL23397291 | 0.87 | PTGS2 (0.33) | NPSR1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL20224059 | 0.85 | L3MBTL1 (0.38) | LPOLMNACYP1A2ALDH1A1TSHR | |
| SCHEMBL23397297 | 0.83 | NOTUM (0.46) | NPSR1LPOLMNACYP1A2ALDH1A1 | |
| SCHEMBL20977770 | 0.80 | KDM4E (0.36) | ALDH1A1HTTKDM4EHPGDELANE | |
| SCHEMBL20224070 | 0.77 | ELANE (0.33) | ALDH1A1ELANENOTUML3MBTL1 | |
| SCHEMBL18054324 | 0.77 | NPSR1 (0.40) | NPSR1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL18054350 | 0.76 | RHEB (0.43) | LMNACYP1A2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL20707566 | 0.75 | ALDH1A1 (0.45) | NPSR1LPOLMNACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016137506-A1 | PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS AND THEIR THERAPEUTICAL APPLICATIONS | NANTBIOSCIENCE, INC. (US) | 2016-09-01 | — | — | WO | disclosed |