Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.32 |
| ▸ | LPO | P22079 | 4/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18054331 | 0.92 | NPSR1 (0.39) | ELANENPSR1POLBCNR2LMNA | |
| SCHEMBL20977770 | 0.89 | KDM4E (0.36) | ELANEPOLBALDH1A1HTTKDM4E | |
| SCHEMBL20224070 | 0.85 | ELANE (0.33) | ELANEALDH1A1NOTUM | |
| SCHEMBL18052960 | 0.83 | KDM4E (0.35) | ELANEPOLBLMNAALDH1A1KDM4E | |
| SCHEMBL23397291 | 0.82 | PTGS2 (0.33) | NPSR1POLBLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18052970 | 0.82 | ALDH1A1 (0.39) | ELANEPOLBLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18054196 | 0.81 | PTGDR2 (0.33) | NPSR1PTGDR2LMNAALDH1A1HTT | |
| SCHEMBL20224059 | 0.79 | L3MBTL1 (0.38) | ELANEPOLBLMNAALDH1A1TSHR | |
| SCHEMBL23397297 | 0.76 | NOTUM (0.46) | ELANENPSR1POLBLMNAALDH1A1 | |
| SCHEMBL20224081 | 0.74 | NOTUM (0.41) | ELANELMNAALDH1A1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016137506-A1 | PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS AND THEIR THERAPEUTICAL APPLICATIONS | NANTBIOSCIENCE, INC. (US) | 2016-09-01 | — | — | WO | disclosed |