SCHEMBL1806101

SCHEMBL1806101

O=S(=O)(O)c1cc(O)c2cc[c]cc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 4/20 0.57
NSD2 O96028 3/20 0.57
DUSP3 P51452 2/20 0.57
PTPN5 P54829 2/20 0.57
PTPN11 Q06124 2/20 0.57
NT5E P21589 3/20 0.53
PRMT1 Q99873 3/20 0.53
CASP7 P55210 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.44
HSD17B10 Q99714 5/20 0.44
ALDH1A1 P00352 4/20 0.44
CYP2C9 P11712 4/20 0.44
CYP2C19 P33261 3/20 0.44
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.41
APEX1 P27695 1/20 0.38
SIRT1 Q96EB6 1/20 0.37
HIF1A Q16665 2/20 0.37
CYP1A2 P05177 2/20 0.36
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1808800 0.88 NT5E (0.55) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL1805276 0.85 CASP6 (0.42) CASP6NSD2DUSP3PTPN5PTPN11
Water SCHEMBL28289812 0.82 CASP6 (0.74) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL29462031 0.80 CASP6 (0.77) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL465086 0.80 CASP6 (0.77) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL1806002 0.79 SNCA (0.47) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL1805049 0.79 ALDH1A1 (0.46) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL18274858 0.78 CASP6 (0.74) CASP6NSD2DUSP3PTPN5PTPN11
Ammonia Solution, Strong SCHEMBL11667165 0.78 CASP6 (0.74) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL1984810 0.78 CASP6 (0.74) CASP6NSD2DUSP3PTPN5PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294853-A1 Bis Aromatic Compounds for Use in the Treatment of Inflammation BIOLIPOX AB (SE) 2011-12-01 US claimed
WO-2010029300-A1 BIS AROMATIC COMPOUNDS FOR USE IN THE TREATMENT OF INFLAMMATION BIOLIPOX AB (SE) 2010-03-18 WO claimed
EP-0476928-A1 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1992-03-25 EP claimed
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110294853-A1 Bis Aromatic Compounds for Use in the Treatment of Inflammation BIOLIPOX AB (SE) 2011-12-01 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed
WO-2010029300-A1 BIS AROMATIC COMPOUNDS FOR USE IN THE TREATMENT OF INFLAMMATION BIOLIPOX AB (SE) 2010-03-18 WO disclosed
US-20050227188-A1 Silver halide photosensitive material and method of forming image KONICA MINOLTA PHOTO IMAGINE, INC. (JP) 2005-10-13 US disclosed
EP-1553443-A1 SILVER HALIDE PHOTOSENSITIVE MATERIAL AND METHOD OF FORMING IMAGE Konica Minolta Photo Imaging, Inc. (JP) 2005-07-13 EP disclosed
WO-1997025472-A1 METHOD OF PRODUCING COLOURED NATURAL OR SYNTHETIC SUBSTRATES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1997-07-17 WO disclosed
EP-0488601-B1 Silver halide photographic light-sensitive material KONISHIROKU PHOTO IND (JP) 1996-07-31 EP disclosed
EP-0476928-A1 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1992-03-25 EP disclosed
US-4996138-A Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1991-02-26 US disclosed
US-4960686-A WATER SOLUBILITY; EASILY ELUTED AFTER DEVELOPMENT KONICA CORPORATION (JP) 1990-10-02 US disclosed
EP-0388908-A1 A silver halide light-sensitive photographic material KONICA CORPORATION (JP) 1990-09-26 EP disclosed
US-4957856-A X-RAY FILMS HAVING A SUBBING LAYER COMPRISING A GELATIN BINDER, A CATIONIC ADDITION COPOLYMER, A PYRAZOLONE DYE AND A NONIONIC SURFACTANT; ANTIHALATION AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1990-09-18 US disclosed
US-4933268-A OXONOL DYE HAVING PYRAZOLONE NUCLEUS FUJI PHOTO FILM CO., LTD. (JP) 1990-06-12 US disclosed
EP-0362734-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1990-04-11 EP disclosed
EP-0361949-A2 Silver halide photographic light-sensitive material containing oxonol dye KONICA CORPORATION (JP) 1990-04-04 EP disclosed
EP-0316013-A2 Silver halide photographic material having at least one dyed hydrophilic colloid layer Fuji Photo Film Co., Ltd. (JP) 1989-05-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 CASP6 4737/4885NSD2 1137/4885DUSP3 4392/4885
US-20110294853-A1 Bis Aromatic Compounds for Use in the Treatment of Inflammation LTC4S, LTB4R2, LTB4R CASP6 1521/4885NSD2 3527/4885DUSP3 2131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.