Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11475054 | 0.87 | KMT2A (0.50) | LMNAMEN1MAPTKMT2AGPR55 | |
| SCHEMBL4946065 | 0.85 | CRHBP (0.44) | CRHBPCRHR2HPGDHSD17B10CYP2C9 | |
| SCHEMBL813137 | 0.83 | CRHBP (0.55) | LMNAMEN1MAPTKMT2AGPR55 | |
| SCHEMBL30444974 | 0.79 | CYP19A1 (0.47) | LMNAMEN1MAPTKMT2ACRHBP | |
| SCHEMBL12726017 | 0.78 | PTGER1 (0.38) | MAPTL3MBTL1TDP1PDCD1CD274 | |
| SCHEMBL24122647 | 0.76 | PDCD1 (0.40) | LMNAMEN1MAPTKMT2AESR2 | |
| SCHEMBL9285749 | 0.76 | ALDH1A1 (0.42) | CRHBPCRHR2CYP19A1HPGDHSD17B10 | |
| SCHEMBL11392792 | 0.76 | RORC (0.43) | MAPTKMT2ACRHBPCRHR2CYP19A1 | |
| SCHEMBL1758324 | 0.75 | CRHBP (0.48) | LMNAMEN1MAPTKMT2AGPR55 | |
| SCHEMBL8785533 | 0.74 | TSHR (0.47) | LMNAMEN1MAPTKMT2AGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9859502-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2018-01-02 | — | — | US | disclosed |
| US-20160268509-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160268509-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, GPX1, EPN1 | LMNA 3763/4885MEN1 345/4885MAPT 2268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.