Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15491545 | 0.81 | DHODH (0.50) | KMT2AALDH1A1HTTMEN1FABP3 | |
| SCHEMBL620402 | 0.81 | KDM4E (0.56) | TP53HSD17B10KMT2AALDH1A1HTT | |
| SCHEMBL10251073 | 0.81 | KMT2A (0.54) | TP53HSD17B10KMT2AALDH1A1HTT | |
| SCHEMBL620119 | 0.79 | HSD17B10 (0.81) | TP53HSD17B10KMT2AALDH1A1HTT | |
| SCHEMBL18080679 | 0.79 | TP53 (0.47) | TP53HSD17B10KMT2AALDH1A1HTT | |
| SCHEMBL19901694 | 0.77 | KDM4E (0.59) | TP53HSD17B10KMT2AALDH1A1MEN1 | |
| SCHEMBL9689780 | 0.74 | GABRP (0.58) | KMT2AALDH1A1MEN1GAAGFER | |
| SCHEMBL15491778 | 0.73 | ALDH1A1 (0.52) | TP53HSD17B10KMT2AALDH1A1HTT | |
| SCHEMBL7648675 | 0.73 | ALDH1A1 (0.56) | TP53HSD17B10KMT2AALDH1A1HTT | |
| SCHEMBL17796019 | 0.72 | PLA2G2A (0.53) | HSD17B10KMT2AALDH1A1MEN1FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160251372-A1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED | 2016-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160251372-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | TP53 2533/4885HSD17B10 1094/4885KMT2A 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.