Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | GLI1 | P08151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2917607 | 0.89 | DPP4 (0.36) | DPP4GLI1TSHR | |
| SCHEMBL8393971 | 0.84 | CHRNB2 (0.31) | — | |
| SCHEMBL2921241 | 0.84 | GLI1 (0.40) | DPP4GLI1TSHR | |
| SCHEMBL12900586 | 0.83 | MMP1 (0.32) | — | |
| SCHEMBL27286359 | 0.80 | CHRNB2 (0.33) | TSHR | |
| SCHEMBL18231611 | 0.79 | DPP4 (0.33) | DPP4GLI1 | |
| SCHEMBL28509881 | 0.79 | DPP4 (0.33) | DPP4GLI1TACR1 | |
| SCHEMBL2916820 | 0.79 | SLC6A1 (0.36) | TSHR | |
| SCHEMBL12108456 | 0.79 | TSHR (0.33) | TSHR | |
| SCHEMBL12524260 | 0.79 | SLC6A1 (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961521-A1 | ASYMMETRICALLY POROUS MEMBRANES MADE OF CROSS-LINKED THERMOPLASTIC SILICONE ELASTOMER | Wacker Chemie AG (DE) | 2016-01-06 | — | — | EP | disclosed |
| WO-2015032286-A1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | F.HOFFMANN-LA ROCHE AG (CH) | 2015-03-12 | — | — | WO | disclosed |
| WO-2014131673-A1 | ASYMMETRICALLY POROUS MEMBRANES MADE OF CROSS-LINKED THERMOPLASTIC SILICONE ELASTOMER | WACKER CHEMIE AG (DE) | 2014-09-04 | — | — | WO | disclosed |
| US-20110269700-A1 | GLUCOSIDE DERIVATIVES AND USES THEREOF | NOVARTIS AG | 2011-11-03 | — | — | US | disclosed |
| US-20110269700-A1 | GLUCOSIDE DERIVATIVES AND USES THEREOF | NOVARTIS AG | 2011-11-03 | — | — | US | disclosed |
| EP-2315626-A1 | POROUS MEMBRANES MADE UP OF ORGANOPOLYSILOXANE COPOLYMERS | Wacker Chemie AG (DE) | 2011-05-04 | — | — | EP | disclosed |
| EP-1591443-B1 | PYRAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-08-25 | — | — | EP | disclosed |
| WO-2010031820-A1 | GLUCOSIDE DERIVATIVES AND USES THEREOF AS SGLT INHIBITORS | NOVARTIS AG (CH) | 2010-03-25 | — | — | WO | disclosed |
| WO-2010020584-A1 | POROUS MEMBRANES MADE UP OF ORGANOPOLYSILOXANE COPOLYMERS | WACKER CHEMIE AG (DE) | 2010-02-25 | — | — | WO | disclosed |
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | disclosed |
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| US-20080064682-A1 | Pyrazole Derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20070254881-A1 | Pyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
| EP-1803719-A1 | 1,5-DIHETEROCYCLE-1H-TRIAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-07-04 | — | — | EP | disclosed |
| EP-1785418-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-05-16 | — | — | EP | disclosed |
| EP-1762568-A1 | PYRAZOLE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-14 | — | — | EP | disclosed |
| US-20060189591-A1 | Five-membered heterocyclic derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| US-20060128685-A1 | Pyrazole derivative | DAIICHI PHARMACEUTICAL CO., LTD., (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1621537-A1 | FIVE-MEMBERED HETEROCYCLIC DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-02-01 | — | — | EP | disclosed |
| EP-1591443-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | PTGS1, PTGER1, TBXA2R | DPP4 3386/4885GLI1 477/4885TSHR 2787/4885 |
| US-20070254881-A1 | Pyrazole Derivative | PTGER1, PTGS1, PTGER2 | DPP4 3499/4885GLI1 1519/4885TSHR 4178/4885 |
| US-20110269700-A1 | GLUCOSIDE DERIVATIVES AND USES THEREOF | SLC5A1, UGGT1, SLC5A2 | DPP4 129/4885GLI1 2523/4885TSHR 3285/4885 |
| US-20060128685-A1 | Pyrazole derivative | PTGS1, PTGS2, PTGER1 | DPP4 440/4885GLI1 1146/4885TSHR 4631/4885 |
| US-20080064682-A1 | Pyrazole Derivatives | NAT1, AR, CBR3 | DPP4 2303/4885GLI1 2064/4885TSHR 2789/4885 |
| US-20060189591-A1 | Five-membered heterocyclic derivative | PTGS1, PTGIS, PTGS2 | DPP4 1243/4885GLI1 690/4885TSHR 4671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.