Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18551705 | 0.84 | L3MBTL1 (0.59) | MAPTL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL4859516 | 0.80 | NPC1 (0.62) | MAPTL3MBTL1ALDH1A1KMT2ANPC1 | |
| SCHEMBL3595754 | 0.79 | RAB9A (0.47) | MAPTL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL395103 | 0.78 | GSK3B (0.48) | MAPTL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL5745992 | 0.78 | GSK3B (0.58) | MAPTL3MBTL1ALDH1A1NPC1MMP1 | |
| SCHEMBL9736095 | 0.76 | NPC1 (0.48) | MAPTL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL135620 | 0.76 | HDAC3 (0.59) | MAPTALDH1A1NPC1MMP1RAB9A | |
| SCHEMBL1879154 | 0.75 | PKM (0.69) | L3MBTL1ALDH1A1GAAPKM | |
| SCHEMBL2092444 | 0.75 | HTT (0.55) | L3MBTL1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL136576 | 0.75 | MMP2 (0.47) | MAPTALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9458161-B1 | TSPO ligands for cancer imaging and treatment | VANDERBLIT UNIVERSITY (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458161-B1 | TSPO ligands for cancer imaging and treatment | VANDERBLIT UNIVERSITY (US) | 2016-10-04 | — | — | US | disclosed |