Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15562756 | 0.78 | APP (0.41) | APPHTR2ATSHRSIGMAR1TDP1 | |
| SCHEMBL15562684 | 0.78 | APP (0.41) | APPHTR2ATSHRSIGMAR1TDP1 | |
| SCHEMBL144604 | 0.76 | MIF (0.40) | APPHTR2ATSHRFFAR1MIF | |
| SCHEMBL7008514 | 0.74 | HTR2A (0.41) | APPHTR2ATSHRSIGMAR1FFAR1 | |
| SCHEMBL3031415 | 0.72 | APP (0.55) | APPHTR2ASIGMAR1NPC1MTOR | |
| SCHEMBL15563018 | 0.71 | HTR2A (0.38) | APPHTR2ATSHRSIGMAR1FFAR1 | |
| SCHEMBL15562779 | 0.71 | HTR2A (0.38) | APPHTR2ASIGMAR1NPC1RAB9A | |
| SCHEMBL15562569 | 0.70 | LMNA (0.39) | APPHTR2ATSHRSIGMAR1FFAR1 | |
| Benzonitrile SCHEMBL9727712 | 0.70 | TSHR (0.70) | APPHTR2ATSHRMAOA | |
| SCHEMBL2710737 | 0.69 | APP (0.43) | APPHTR2ATSHRNPC1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 448 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027620-B1 | 2,2,6,6-TETRAALKYL-4-PIPERIDYL-BIS-SPIRO-ETHERS AND SYNTHETIC POLYMERS STABILISED THEREWITH | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1985-07-24 | — | — | EP | claimed |
| US-20240084308-A1 | FIBROTIC TREATMENT | MONASH UNIVERSITY (AU) | 2024-03-14 | — | — | US | disclosed |
| US-20240034845-A1 | POLYMER PARTICLES | QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) | 2024-02-01 | — | — | US | disclosed |
| EP-3384549-B1 | SODIUM-ION ELECTROLYTE COMPOSITION | UNIV DEAKIN (AU) | 2024-01-17 | — | — | EP | disclosed |
| US-11834663-B2 | Fibrotic treatment | MONASH UNIVERSITY (AU) | 2023-12-05 | — | — | US | disclosed |
| US-20230348674-A1 | HYDROGELS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2023-11-02 | — | — | US | disclosed |
| EP-4225811-A1 | POLYMER PARTICLES | Queensland University Of Technology (AU) | 2023-08-16 | — | — | EP | disclosed |
| WO-2023121483-A1 | IMMUNOSTIMULATORY COMPOSITIONS | VICTORIA LINK LIMITED (NZ) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023102600-A1 | SYNTHESIS OF AMPHIPHILIC BLOCK COPOLYMERS AND POLYMERIC NANOFIBERS PRODUCED THEREFROM | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023099589-A1 | IRAP INHIBITORS FOR USE IN THE TREATMENT OF INFLAMMATORY DISEASES | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2023-06-08 | — | — | WO | disclosed |
| EP-0395030-A1 | Polyolefin resins containing ziegler type complex catalyst residues stabilized with organic phosphites | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1990-10-31 | — | — | EP | disclosed |
| EP-0360079-A1 | Tricyclic compounds, processes for their preparation and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-28 | — | — | EP | disclosed |
| EP-0336230-A2 | Cyclic peptide antagonists of Substance P and Substance K | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-10-11 | — | — | EP | disclosed |
| US-4735959-A | HYPOGLYCEMIC AGENTS | DR. KARL THOMAE GMBH (DE) | 1988-04-05 | — | — | US | disclosed |
| EP-0128229-B1 | HINDERED BISPHENOL DIPHOSPHONITES AND STABILIZED SYNTHETIC RESIN COMPOSITIONS CONTAINING THE SAME | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1987-09-16 | — | — | EP | disclosed |
| EP-0032681-B1 | HINDERED BIS-PHENOL PHENYL PHOSPHITES AND SYNTHETIC RESIN COMPOSITIONS HAVING ENHANCED STABILITY TO HEAT AND LIGHT | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1987-07-22 | — | — | EP | disclosed |
| US-4670492-A | Cyclic bis and tris phosphites and stabilized synthetic resin compositions | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1987-06-02 | — | — | US | disclosed |
| EP-0128229-A1 | Hindered bisphenol diphosphonites and stabilized synthetic resin compositions containing the same | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1984-12-19 | — | — | EP | disclosed |
| US-4481317-A | HEAT RESISTANCE | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1984-11-06 | — | — | US | disclosed |
| US-4362830-A | Hindered bis-phenol phenyl phosphites and synthetic resin compositions having enhanced stability to heat and light | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1982-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11834663-B2 | Fibrotic treatment | MMP1, ENPEP, RNPEP | APP 1687/4885HTR2A 4496/4885TSHR 2551/4885 |
| US-20230348674-A1 | HYDROGELS | PHYKPL, TST, PHOSPHO1 | APP 4766/4885HTR2A 3468/4885TSHR 1684/4885 |
| US-20240084308-A1 | FIBROTIC TREATMENT | MMP1, ENPEP, RNPEP | APP 1687/4885HTR2A 4496/4885TSHR 2551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.