Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 8/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12117309 | 0.97 | KDM4E (0.36) | GPR3KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL18056702 | 0.95 | GPR3 (0.47) | GPR3KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL14073457 | 0.88 | GPR3 (0.36) | GPR3KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL17381254 | 0.83 | KDM4E (0.44) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL16696176 | 0.83 | MEN1 (0.40) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6123861 | 0.83 | L3MBTL1 (0.43) | KDM4EALDH1A1L3MBTL1HPGDHSD17B10 | |
| SCHEMBL13427220 | 0.82 | P2RX4 (0.36) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12117311 | 0.80 | L3MBTL1 (0.41) | KDM4EALDH1A1L3MBTL1HPGDHSD17B10 | |
| SCHEMBL17381320 | 0.80 | MAPT (0.51) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL16696175 | 0.80 | MEN1 (0.46) | MAPTALDH1A1HPGDMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2018-07-26 | — | — | US | disclosed |
| US-20160301015-A1 | LIGHT-EMITTING COMPOUNDS FOR LIGHT-EMITTING DEVICES | NITTO DENKO CORPORATION (JP) | 2016-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | MSN, DDT, NECTIN4 | GPR3 2683/4885KDM4E 2444/4885MAPT 609/4885 |
| US-20160301015-A1 | LIGHT-EMITTING COMPOUNDS FOR LIGHT-EMITTING DEVICES | CRY1, ALDH1A2, CRY2 | GPR3 2778/4885KDM4E 3735/4885MAPT 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.