Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18138249 | 0.82 | CNR2 (0.35) | ALDH1A1KMT2AHDAC3HDAC8NCOR2 | |
| SCHEMBL18138297 | 0.74 | GSK3B (0.33) | KMT2AHDAC3HDAC8NCOR2GSK3B | |
| SCHEMBL24828638 | 0.70 | RAB9A (0.49) | ALDH1A1KMT2A | |
| SCHEMBL24896677 | 0.68 | L3MBTL1 (0.46) | ALDH1A1KMT2AHDAC3HDAC8NCOR2 | |
| SCHEMBL24828548 | 0.67 | DRD2 (0.37) | DRD2GFERHDAC3HDAC8NCOR2 | |
| SCHEMBL25360606 | 0.67 | GSK3B (0.38) | DRD2GSK3BDYRK1A | |
| SCHEMBL18138240 | 0.67 | FGFR1 (0.31) | ALDH1A1KMT2A | |
| SCHEMBL24506914 | 0.67 | SLC34A1 (0.46) | DRD2 | |
| SCHEMBL22858331 | 0.67 | AAK1 (0.39) | DRD2ALDH1A1KMT2AGFEROPRM1 | |
| SCHEMBL19026780 | 0.66 | RAB9A (0.36) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016164754-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-10-13 | — | — | WO | disclosed |