Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18138241 | 0.78 | NOTUM (0.35) | PDE10A | |
| SCHEMBL18138235 | 0.75 | ALDH1A1 (0.40) | ADORA3ALDH1A1SMN1; SMN2 | |
| SCHEMBL18138285 | 0.73 | LMNA (0.35) | MEN1ALDH1A1KMT2ASMN1; SMN2PDE10A | |
| SCHEMBL24612004 | 0.72 | NOTUM (0.42) | HDAC1HDAC2PDE10A | |
| SCHEMBL18412911 | 0.71 | CRHR1 (0.35) | FGFR1FGFR2FGFR3HDAC1HDAC2 | |
| SCHEMBL28170670 | 0.67 | BRD4 (0.36) | MEN1ALDH1A1KMT2A | |
| SCHEMBL18138239 | 0.67 | DRD2 (0.39) | ALDH1A1KMT2A | |
| SCHEMBL21087670 | 0.67 | LRRK2 (0.40) | ADORA3MEN1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL15650720 | 0.67 | MAPT (0.36) | MEN1ALDH1A1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL31352232 | 0.67 | LMNA (0.38) | ADORA3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016164754-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-10-13 | — | — | WO | disclosed |