Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
| ▸ | MMP8 | P22894 | 3/20 | 0.34 |
| ▸ | MMP13 | P45452 | 3/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18131174 | 0.94 | MMP1 (0.35) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL18138290 | 0.88 | IRAK4 (0.35) | GSTP1GSTM2PRMT1ALDH1A1BRD4 | |
| SCHEMBL18138300 | 0.85 | PRMT1 (0.35) | GSTP1GSTM2PRMT1ALDH1A1BRD4 | |
| SCHEMBL18138287 | 0.84 | DUT (0.34) | GSTP1GSTM2PRMT1ALDH1A1BRD4 | |
| SCHEMBL18138228 | 0.83 | LMNA (0.37) | GSTP1GSTM2PRMT1ALDH1A1 | |
| SCHEMBL18138351 | 0.83 | PRMT1 (0.36) | GSTP1GSTM2PRMT1ALDH1A1BRD4 | |
| SCHEMBL18138301 | 0.82 | ALDH1A1 (0.35) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL18138283 | 0.80 | PRMT1 (0.34) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL18138350 | 0.80 | GSTP1 (0.33) | GSTP1GSTM2PRMT1ALDH1A1BRD4 | |
| SCHEMBL18131172 | 0.80 | PRMT1 (0.36) | MMP1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016164754-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-10-13 | — | — | WO | disclosed |