SCHEMBL18152

SCHEMBL18152

COc1cccc(S(=O)(=O)Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 8/20 0.53
KEAP1 Q14145 2/20 0.53
FFAR4 Q5NUL3 1/20 0.53
PGR P06401 3/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
ENPP2 Q13822 1/20 0.50
MEP1B Q16820 1/20 0.49
TAS2R14 Q9NYV8 1/20 0.48
GAA P10253 1/20 0.48
ACHE P22303 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anisole SCHEMBL3035093 0.93 TAS2R14 (0.54) NFE2L2KEAP1FFAR4PGRENPP2
SCHEMBL14120564 0.89 PTGES2 (0.52) NFE2L2KEAP1FFAR4PGRCA12
SCHEMBL14572638 0.88 PGR (0.58) NFE2L2KEAP1PGRENPP2TAS2R14
SCHEMBL31352975 0.83 MTNR1B (0.56) NFE2L2KEAP1FFAR4PGRCA12
SCHEMBL3151230 0.83 MTNR1B (0.56) NFE2L2KEAP1FFAR4PGRCA12
1,3-Dimethoxybenzene SCHEMBL2179669 0.83 ACHE (0.54) NFE2L2PGRCA12CA1CA2
SCHEMBL11155550 0.82 NFE2L2 (0.54) NFE2L2KEAP1FFAR4PGRCA12
Anisole SCHEMBL22187427 0.82 ALDH1A1 (0.67) PGRTAS2R14GAA
SCHEMBL803706 0.82 NFE2L2 (0.54) NFE2L2KEAP1FFAR4PGRCA12
SCHEMBL29650302 0.82 NFE2L2 (0.54) NFE2L2KEAP1FFAR4PGRCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115925606-B 5- (3- (sulfonamide) phenyl) -1H-pyrrole-2-carboxylic acid derivative and preparation method and application thereof 宁夏医科大学 2023-10-13 CN claimed
CN-115193419-B Magnetic microsphere, preparation method, application and diagnostic kit thereof 苏州纳微生命科技有限公司 2022-11-22 CN claimed
CN-115193419-A Magnetic microsphere, preparation method, application and diagnostic kit thereof 苏州纳微生命科技有限公司 2022-10-18 CN claimed
CN-104678028-A Pretreatment and detection method for biogen amine neurotransmitter and detection kit INST PHARM & TOXICOLOGY AMMS 2015-06-03 CN claimed
EP-1506176-B1 AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM PFIZER ITALIA SRL (IT) 2013-04-24 EP claimed
EP-2385831-A2 SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT The UAB Research Foundation (US) 2011-11-16 EP claimed
US-20110254866-A1 INFORMATION PROCESSING APPARATUS, METHOD AND PROGRAM THEREFORE SONY CORPORATION (JP) 2011-10-20 US claimed
WO-2010123591-A2 SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT THE UAB RESEARCH FOUNDATION (US) 2010-10-28 WO claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
CN-117659017-B TRPML1/2 modulator compound, pharmaceutical composition, preparation method and application thereof 北京华益健康药物研究中心 2026-05-15 CN disclosed
CN-122010862-A Novel PET tracer agent targeting cannabinoid type 2 receptor and preparation method thereof 杭州吉蕊科技有限公司 2026-05-12 CN disclosed
WO-2026087635-A1 DIHYDRO BENZOXAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-04-30 WO disclosed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 US disclosed
EP-4712958-A2 USE OF UROLITHIN DERIVATIVES IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS Vandria SA (CH) 2026-03-25 EP disclosed
US-4443477-A ANTICOAGULANTS, ANTILIPEMIC AGENTS BOEHRINGER MANNHEIM GMBH (DE) 1984-04-17 US disclosed
EP-0038458-B1 4-HYDROXY-1,2-BENZISOTHIAZOL-3(2H)-ONE-1,1-DIOXIDE, THEIR SALTS, THEIR PREPARATION AND THEIR UTILIZATION Dr. Karl Thomae GmbH (DE) 1983-09-21 EP disclosed
US-4404230-A ARTICIFIAL SWEETENERS DR. KARL THOMAE GMBH (DE) 1983-09-13 US disclosed
EP-0038458-A1 4-Hydroxy-1,2-benzisothiazol-3(2H)-one-1,1-dioxide, their salts, their preparation and their utilization Dr. Karl Thomae GmbH (DE) 1981-10-28 EP disclosed
US-4131680-A Hypotensive sulphonamidopiperidyl indoles JOHN WYETH & BROTHER LTD. (GB) 1978-12-26 US disclosed
US-3947471-A CHROMOGENIC SUMITOMO CHEMICAL COMPANY, LTD. (JA) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 NFE2L2 1608/4885KEAP1 2197/4885FFAR4 2090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.