Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18152633 | 0.81 | USP30 (0.34) | SCN9AGRIN1GRIN2BALDH1A1HPGD | |
| SCHEMBL18152627 | 0.79 | CCNB2 (0.31) | — | |
| SCHEMBL18152783 | 0.71 | RIPK1 (0.33) | MAPTHPGDHSD17B10 | |
| SCHEMBL18152659 | 0.70 | ADRB2 (0.33) | — | |
| SCHEMBL18152677 | 0.66 | CCNB2 (0.32) | — | |
| SCHEMBL18152712 | 0.63 | GRIN2D (0.38) | GRIN1GRIN2BMAPT | |
| SCHEMBL18152668 | 0.62 | HTT (0.31) | — | |
| SCHEMBL18152624 | 0.62 | HTT (0.33) | — | |
| SCHEMBL6500700 | 0.60 | EGLN1 (0.40) | HPGDSMN1; SMN2 | |
| SCHEMBL17813560 | 0.56 | BRD4 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283077-A2 | BROMODOMAIN INHIBITOR | Celgene Quanticel Research, Inc. (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168682-A2 | BROMODOMAIN INHIBITOR | CELGENE QUANTICEL RESEARCH, INC. (US) | 2016-10-20 | — | — | WO | disclosed |