Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.58 |
| ▸ | MMP1 | P03956 | 5/20 | 0.57 |
| ▸ | MMP9 | P14780 | 5/20 | 0.57 |
| ▸ | MMP3 | P08254 | 4/20 | 0.57 |
| ▸ | MMP7 | P09237 | 4/20 | 0.57 |
| ▸ | STS | P08842 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKLR | P30613 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 4/20 | 0.44 |
| ▸ | F13A1 | P00488 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18153290 | 0.82 | PKM (0.66) | MMP1MMP9MMP3MMP7STS | |
| SCHEMBL1665532 | 0.78 | ALDH1A1 (0.53) | MMP1MMP9MMP3MMP7STS | |
| SCHEMBL2262766 | 0.78 | CYP3A4 (0.52) | MMP1MMP9MMP3MMP7STS | |
| SCHEMBL22127635 | 0.76 | MAPT (0.55) | MMP1MMP9MMP3MMP7STS | |
| SCHEMBL18162515 | 0.75 | MMP2 (0.70) | MMP2ALDH1A1PKMNPC1PKLR | |
| SCHEMBL17102066 | 0.74 | STS (0.55) | MMP2MMP1MMP9MMP3MMP7 | |
| SCHEMBL7375156 | 0.74 | MMP1 (0.77) | MMP1MMP9MMP3MMP7STS | |
| SCHEMBL8294396 | 0.74 | MMP1 (0.47) | MMP1MMP9MMP3MMP7STS | |
| SCHEMBL17100709 | 0.74 | CYP3A4 (0.60) | MMP1MMP9MMP3MMP7STS | |
| SCHEMBL23329646 | 0.73 | STS (0.65) | MMP2MMP1MMP9MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283472-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | Indiana University Research&Technology Corporation (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168619-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-10-20 | — | — | WO | disclosed |
| WO-2016168619-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-10-20 | — | — | WO | disclosed |