Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 5/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166307 | 0.92 | MARS1 (0.37) | MARS1F2MEN1KMT2ADGAT2 | |
| SCHEMBL18166440 | 0.91 | MARS1 (0.40) | MARS1F2MEN1KMT2ADGAT2 | |
| SCHEMBL10243038 | 0.87 | MARS1 (0.47) | MARS1F2MEN1KMT2ATBXA2R | |
| SCHEMBL18166327 | 0.85 | ROCK1 (0.39) | DGAT2ROCK2ROCK1KCNA5LMNA | |
| SCHEMBL18166443 | 0.85 | MARS1 (0.43) | MARS1MEN1KMT2AMAPTF11 | |
| SCHEMBL18166303 | 0.85 | ROCK1 (0.39) | F2KMT2ADGAT2ROCK2ROCK1 | |
| SCHEMBL18166321 | 0.84 | KMT2A (0.44) | KMT2ADGAT2ROCK2ROCK1 | |
| SCHEMBL18166354 | 0.83 | KMT2A (0.38) | F2MEN1KMT2ADGAT2ROCK2 | |
| SCHEMBL18166314 | 0.83 | ROCK1 (0.40) | F2MEN1KMT2ADGAT2ROCK2 | |
| SCHEMBL18036409 | 0.82 | LMNA (0.42) | MARS1F2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |