SCHEMBL181670

SCHEMBL181670

CC1(C)C(=O)N(C2CCN(C(=O)C(CCc3ccccc3)NC(=O)C3CCCNC3)CC2)c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MC4R P32245 7/20 0.44
MC5R P33032 1/20 0.44
MC3R P41968 1/20 0.44
MC1R Q01726 1/20 0.44
CCKBR P32239 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 2/20 0.40
CALCRL Q16602 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
GHSR Q92847 2/20 0.36
F2 P00734 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
CCR1 P32246 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL181669 1.00 MC4R (0.44) MC4RMC5RMC3RMC1RCCKBR
SCHEMBL29160493 1.00 MC4R (0.44) MC4RMC5RMC3RMC1RCCKBR
SCHEMBL13185979 1.00 MC4R (0.44) MC4RMC5RMC3RMC1RCCKBR
SCHEMBL30778907 1.00 MC4R (0.44) MC4RMC5RMC3RMC1RCCKBR
SCHEMBL30778916 1.00 MC4R (0.44) MC4RMC5RMC3RMC1RCCKBR
SCHEMBL15640877 1.00 MC4R (0.44) MC4RMC5RMC3RMC1RCCKBR
Hydrochloric Acid SCHEMBL29160491 0.99 MC4R (0.43) MC4RMC5RMC3RMC1RCCKBR
Hydrochloric Acid SCHEMBL29160492 0.99 MC4R (0.43) MC4RMC5RMC3RMC1RCCKBR
Hydrochloric Acid SCHEMBL29160494 0.99 MC4R (0.43) MC4RMC5RMC3RMC1RCCKBR
Sulfuric Acid SCHEMBL29160497 0.97 MC4R (0.42) MC4RMC5RMC3RMC1RCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146036-A1 CRYSTALLINE FORMS RAQUALIA PHARMA INC. (JP) 2026-05-28 US claimed
EP-4377309-B1 CRYSTALLINE FORMS RAQUALIA PHARMA INC (JP) 2026-05-20 EP claimed
US-20240351998-A1 CRYSTALLINE FORMS RAQUALIA PHARMA INC. (JP) 2024-10-24 US claimed
EP-4377309-A1 CRYSTALLINE FORMS RaQualia Pharma Inc. (JP) 2024-06-05 EP claimed
CN-117616022-A Crystalline forms 拉夸里亚创药株式会社 2024-02-27 CN claimed
WO-2023008585-A1 CRYSTALLINE FORMS RAQUALIA PHARMA INC. (JP) 2023-02-02 WO claimed
EP-2401268-B1 OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY RAQUALIA PHARMA INC (JP) 2015-07-29 EP claimed
US-8697877-B2 Oxyindole derivatives with motilin receptor agonistic activity RAQUALIA PHARMA INC. (JP) 2014-04-15 US claimed
EP-2401268-A1 OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY RaQualia Pharma Inc (JP) 2012-01-04 EP claimed
US-20110312933-A1 OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY RAQUALIA PHARMA INC. (JP) 2011-12-22 US claimed
WO-2010098145-A1 OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY RAQUALIA PHARMA INC. (JP) 2010-09-02 WO claimed
US-20260146036-A1 CRYSTALLINE FORMS RAQUALIA PHARMA INC. (JP) 2026-05-28 US disclosed
EP-4377309-B1 CRYSTALLINE FORMS RAQUALIA PHARMA INC (JP) 2026-05-20 EP disclosed
US-12552776-B2 Crystalline forms RAQUALIA PHARMA INC. (JP) 2026-02-17 US disclosed
US-20240351998-A1 CRYSTALLINE FORMS RAQUALIA PHARMA INC. (JP) 2024-10-24 US disclosed
EP-2401268-B1 OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY RAQUALIA PHARMA INC (JP) 2015-07-29 EP disclosed
US-8697877-B2 Oxyindole derivatives with motilin receptor agonistic activity RAQUALIA PHARMA INC. (JP) 2014-04-15 US disclosed
EP-2401268-A1 OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY RaQualia Pharma Inc (JP) 2012-01-04 EP disclosed
US-20110312933-A1 OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY RAQUALIA PHARMA INC. (JP) 2011-12-22 US disclosed
WO-2010098145-A1 OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY RAQUALIA PHARMA INC. (JP) 2010-09-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552776-B2 Crystalline forms MLNR, SIGMAR1, PROKR1 MC4R 188/4885MC5R 351/4885MC3R 111/4885
US-20110312933-A1 OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY GPR68, GPR88, GPR52 MC4R 16/4885MC5R 15/4885MC3R 24/4885
US-20260146036-A1 CRYSTALLINE FORMS PRKCD, CCT8, CRYZ MC4R 3906/4885MC5R 4465/4885MC3R 4383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.