Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.39 |
| ▸ | AHR | P35869 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.35 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.35 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.35 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.35 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.35 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5877432 | 0.88 | ALDH1A1 (0.65) | ALDH1A1CYP1A1CYP1B1AHRCYP1A2 | |
| SCHEMBL21263 | 0.85 | ALDH1A1 (0.69) | ALDH1A1CYP1A1CYP1B1AHRCYP1A2 | |
| SCHEMBL1816933 | 0.83 | ALDH1A1 (0.65) | ALDH1A1CYP1A1CYP1B1AHRCYP1A2 | |
| SCHEMBL177674 | 0.83 | TSHR (0.47) | ALDH1A1AHRCYP3A4CYP2C19IDO1 | |
| SCHEMBL14551872 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP1A1CYP1B1AHRCYP1A2 | |
| SCHEMBL811578 | 0.80 | ALDH1A1 (0.59) | ALDH1A1CYP1A1CYP1B1AHRCYP1A2 | |
| SCHEMBL14120989 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CYP1A1CYP1B1AHRCYP1A2 | |
| SCHEMBL4043764 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP1A1CYP1B1AHRCYP1A2 | |
| SCHEMBL3541751 | 0.77 | RAPGEF4 (0.32) | ALDH1A1CYP3A4 | |
| SCHEMBL6732214 | 0.73 | ALDH1A1 (0.40) | ALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360095-A1 | NOVEL KINASE MODULATORS | RHIZEN PHARMACEUTICALS AG (CH) | 2024-10-31 | — | — | US | disclosed |
| US-10442783-B2 | 2,3-disubstituted chromen-4-one compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2019-10-15 | — | — | US | disclosed |
| EP-2943474-B1 | BIARYL- OR HETEROCYCLIC BIARYL-SUBSTITUTED CYCLOHEXENE DERIVATIVE COMPOUNDS AS CETP INHIBITORS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2017-07-05 | — | — | EP | disclosed |
| US-9493430-B2 | Biaryl- or heterocyclic biaryl-substituted cyclohexene derivative compounds as CETP inhibitors | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2016-11-15 | — | — | US | disclosed |
| US-9421209-B2 | Kinase modulators | RHIZEN PHARMACEUTICALS SA (CH) | 2016-08-23 | — | — | US | disclosed |
| US-20160237046-A9 | Biaryl- or Heterocyclic Biaryl-Substituted Cyclohexene Derivative Compounds as CETP Inhibitors | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2016-08-18 | — | — | US | disclosed |
| EP-2943474-A1 | BIARYL- OR HETEROCYCLIC BIARYL-SUBSTITUTED CYCLOHEXENE DERIVATIVE COMPOUNDS AS CETP INHIBITORS | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-11-18 | — | — | EP | disclosed |
| US-20150322023-A1 | Biaryl- or Heterocyclic Biaryl-Substituted Cyclohexene Derivative Compounds as CETP Inhibitors | CHONG KUN DANG PHARM CORP (KR) | 2015-11-12 | — | — | US | disclosed |
| US-20150174131-A1 | NOVEL KINASE MODULATORS | RHIZEN PHARMACEUTICALS AG (CH) | 2015-06-25 | — | — | US | disclosed |
| US-9018375-B2 | Substituted chromenes as kinase modulators | RHIZEN PHARMACEUTICALS SA (CH) | 2015-04-28 | — | — | US | disclosed |
| WO-2014119947-A1 | BIARYL- OR HETEROCYCLIC BIARYL-SUBSTITUTED CYCLOHEXENE DERIVATIVE COMPOUNDS AS CETP INHIBITORS | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2014-08-07 | — | — | WO | disclosed |
| US-20140080827-A1 | NOVEL KINASE MODULATORS | RHIZEN PHARMACEUTICALS SA (CH) | 2014-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10442783-B2 | 2,3-disubstituted chromen-4-one compounds as modulators of protein kinases | PIK3CB, PIK3CD, PDPK1 | ALDH1A1 4410/4885CYP1A1 3936/4885CYP1B1 3475/4885 |
| US-20150174131-A1 | NOVEL KINASE MODULATORS | PRKCA, PRKCH, PRKCB | ALDH1A1 4305/4885CYP1A1 4693/4885CYP1B1 4580/4885 |
| US-20240360095-A1 | NOVEL KINASE MODULATORS | PRKCA, PRKCH, PRKCB | ALDH1A1 4305/4885CYP1A1 4693/4885CYP1B1 4580/4885 |
| US-20140080827-A1 | NOVEL KINASE MODULATORS | PRKCA, PRKCH, PRKCB | ALDH1A1 4305/4885CYP1A1 4693/4885CYP1B1 4580/4885 |
| US-20160237046-A9 | Biaryl- or Heterocyclic Biaryl-Substituted Cyclohexene Derivative Compounds as CETP Inhibitors | CETP, LIPC, PCSK9 | ALDH1A1 3741/4885CYP1A1 539/4885CYP1B1 374/4885 |
| US-20150322023-A1 | Biaryl- or Heterocyclic Biaryl-Substituted Cyclohexene Derivative Compounds as CETP Inhibitors | CETP, LIPC, PCSK9 | ALDH1A1 3741/4885CYP1A1 539/4885CYP1B1 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.