Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20959894 | 1.00 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2HTTKDM4E | |
| Hydrochloric Acid SCHEMBL3363220 | 0.99 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2HTTKDM4E | |
| SCHEMBL20959900 | 0.96 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2HTTKDM4E | |
| SCHEMBL18166480 | 0.84 | HDAC6 (0.46) | MEN1KMT2ASMN1; SMN2HTTKDM4E | |
| SCHEMBL18170343 | 0.84 | HDAC6 (0.46) | MEN1KMT2ASMN1; SMN2HTTKDM4E | |
| SCHEMBL18170344 | 0.84 | HDAC6 (0.46) | MEN1KMT2ASMN1; SMN2HTTKDM4E | |
| SCHEMBL18184323 | 0.84 | HDAC6 (0.46) | MEN1KMT2ASMN1; SMN2HTTKDM4E | |
| SCHEMBL25968480 | 0.82 | KDM4E (0.52) | MEN1KMT2ASMN1; SMN2HTTKDM4E | |
| SCHEMBL16884338 | 0.81 | SCN9A (0.46) | MEN1KMT2ASMN1; SMN2HTTKDM4E | |
| SCHEMBL3360559 | 0.80 | TRPV6 (0.67) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085688-B1 | ADAMANTANE OR PINENE DERIVATIVES FOR USE IN THE TREATMENT OF CHLAMYDIALES INFECTIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2020-08-19 | — | — | EP | claimed |
| EP-3239131-A1 | NEW COMPOUNDS WITH ACTIVITY THAT PROTECTS AGAINST THE ACTION OF TOXINS AND VIRUSES IN INTRACELLULAR ACTION MODE | Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) | 2017-11-01 | — | — | EP | claimed |
| US-20170233386-A1 | Compounds Which Have a Protective Activity with Respect to the Action of Toxins and of Viruses with an Intracellular Mode of Action | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-08-17 | — | — | US | claimed |
| US-20160310448-A1 | Adamantane or Pinene Derivatives for Use in the Treatment of Chlamydiales Infections | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2016-10-27 | — | — | US | claimed |
| US-20160083355-A1 | COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2016-03-24 | — | — | US | claimed |
| US-20120283249-A1 | Novel compounds which have a protective activity with respect to the action of toxins and of viruses with an intracellular mode of action | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2012-11-08 | — | — | US | claimed |
| EP-2145873-A1 | New compounds with activity that protects against the action of toxins and viruses in intracellular action mode | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2010-01-20 | — | — | EP | claimed |
| EP-3085688-B1 | ADAMANTANE OR PINENE DERIVATIVES FOR USE IN THE TREATMENT OF CHLAMYDIALES INFECTIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2020-08-19 | — | — | EP | disclosed |
| EP-3085688-B1 | ADAMANTANE OR PINENE DERIVATIVES FOR USE IN THE TREATMENT OF CHLAMYDIALES INFECTIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2020-08-19 | — | — | EP | disclosed |
| EP-3476389-A1 | ADAMANTANE OR BICYCLIC MONOTERPENOID DERIVATIVES FOR USE IN THE TREATMENT OF LEISHMANIASIS | Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) | 2019-05-01 | — | — | EP | disclosed |
| US-10039727-B2 | Adamantane or pinene derivatives for use in the treatment of chlamydiales infections | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2018-08-07 | — | — | US | disclosed |
| US-10039727-B2 | Adamantane or pinene derivatives for use in the treatment of chlamydiales infections | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2018-08-07 | — | — | US | disclosed |
| US-10039727-B2 | Adamantane or pinene derivatives for use in the treatment of chlamydiales infections | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2018-08-07 | — | — | US | disclosed |
| US-20160083355-A1 | COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2016-03-24 | — | — | US | disclosed |
| US-20160083355-A1 | COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2016-03-24 | — | — | US | disclosed |
| US-20160083355-A1 | COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2016-03-24 | — | — | US | disclosed |
| US-20120283249-A1 | Novel compounds which have a protective activity with respect to the action of toxins and of viruses with an intracellular mode of action | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2012-11-08 | — | — | US | disclosed |
| US-20120283249-A1 | Novel compounds which have a protective activity with respect to the action of toxins and of viruses with an intracellular mode of action | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2012-11-08 | — | — | US | disclosed |
| US-20120283249-A1 | Novel compounds which have a protective activity with respect to the action of toxins and of viruses with an intracellular mode of action | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2012-11-08 | — | — | US | disclosed |
| EP-2145873-A1 | New compounds with activity that protects against the action of toxins and viruses in intracellular action mode | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2010-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10039727-B2 | Adamantane or pinene derivatives for use in the treatment of chlamydiales infections | ADRA1A, ADRA1B, ADRA1D | MEN1 3852/4885KMT2A 4680/4885SMN1; SMN2 3400/4885 |
| US-20120283249-A1 | Novel compounds which have a protective activity with respect to the action of toxins and of viruses with an intracellular mode of action | HAVCR2, MAVS, ANTXR2 | MEN1 3020/4885KMT2A 4248/4885SMN1; SMN2 3101/4885 |
| US-20160083355-A1 | COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION | HAVCR2, MAVS, ANTXR2 | MEN1 2389/4885KMT2A 4212/4885SMN1; SMN2 3088/4885 |
| US-20170233386-A1 | Compounds Which Have a Protective Activity with Respect to the Action of Toxins and of Viruses with an Intracellular Mode of Action | HAVCR2, MAVS, ANTXR2 | MEN1 2389/4885KMT2A 4212/4885SMN1; SMN2 3088/4885 |
| US-20160310448-A1 | Adamantane or Pinene Derivatives for Use in the Treatment of Chlamydiales Infections | ADRA1A, ADRA1B, ADRA1D | MEN1 3704/4885KMT2A 4734/4885SMN1; SMN2 3512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.