SCHEMBL1817035

SCHEMBL1817035

CCCCCCCCCCCCCCOC(CCN)OCCCCCCCCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 9/20 0.55
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
EPHX1 P07099 1/20 0.44
CA1 P00915 8/20 0.42
CA2 P00918 8/20 0.42
CA9 Q16790 7/20 0.42
CA12 O43570 3/20 0.42
CA7 P43166 3/20 0.42
CA14 Q9ULX7 3/20 0.42
CA3 P07451 2/20 0.42
CA4 P22748 2/20 0.42
CA6 P23280 2/20 0.42
CA5A P35218 2/20 0.42
CA5B Q9Y2D0 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4275158 1.00 DNM1 (0.55) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL4271916 1.00 DNM1 (0.55) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL10384072 1.00 DNM1 (0.55) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL8432808 1.00 DNM1 (0.55) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL4280442 1.00 DNM1 (0.55) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL4275678 1.00 DNM1 (0.55) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL27815332 1.00 DNM1 (0.55) DNM1MEN1KMT2AALDH1A1TSHR
Bromide SCHEMBL5500592 0.98 DNM1 (0.53) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL6577557 0.91 DNM1 (0.43) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL3244710 0.89 DNM1 (0.53) DNM1MEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608877-A1 VARIANT RNA-GUIDED CAS12F4 NUCLEASES AND DNA BINDING PROTEINS Inari Agriculture Technology, Inc. (US) 2025-09-03 EP disclosed
WO-2024091775-A1 VARIANT RNA-GUIDED CAS12F4 NUCLEASES AND DNA BINDING PROTEINS INARI AGRICULTURE TECHNOLOGY, INC. (US) 2024-05-02 WO disclosed
WO-2024030437-A1 FUNCTIONALIZED AND CROSSLINKED POLYMER METHODS AND COMPOSITIONS PMIDG, LLC (US) 2024-02-08 WO disclosed
WO-2024008967-A1 LIPID NANOPARTICLES COMPRISING AN IMIDAZOLIUM-BASED CATIONIC LIPID POLYPLUS TRANSFECTION (FR) 2024-01-11 WO disclosed
WO-2023148276-A1 AGENTS AND METHODS FOR TARGETED DELIVERY TO CELLS BioNTech SE (DE) 2023-08-10 WO disclosed
WO-2023148277-A1 AGENTS AND METHODS FOR TARGETED DELIVERY OF NUCLEIC ACIDS TO CELLS BioNTech SE (DE) 2023-08-10 WO disclosed
US-11510988-B2 Targeting aminoacid lipids MERCK PATENT GMBH (DE) 2022-11-29 US disclosed
EP-3935156-A1 CRISPR-CAS EFFECTOR POLYPEPTIDES AND METHODS OF USE THEREOF The Regents of The University of California (US) 2022-01-12 EP disclosed
EP-3625342-A1 SYSTEMS, METHODS, AND COMPOSITIONS FOR TARGETED NUCLEIC ACID EDITING The Broad Institute, Inc. (US) 2020-03-25 EP disclosed
EP-3455357-A1 TYPE VI CRISPR ORTHOLOGS AND SYSTEMS The Broad Institute Inc. (US) 2019-03-20 EP disclosed
WO-2016079197-A1 DELIVERY ENHANCERS FOR CONJUGATED SIRNA AND LIPID NANOPARTICLES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-05-26 WO disclosed
US-20160090593-A1 Lipid Formulated Compositions And Methods For Inhibiting Expression Of Transthyretin (TTR) ALNYLAM PHARMACEUTICALS, INC. 2016-03-31 US disclosed
US-20160076029-A1 siRNA Therapy for Transthyretin (TTR) Related Ocular Amyloidosis ALNYLAM PHARMACEUTICALS, INC. 2016-03-17 US disclosed
US-20150050295-A9 NOVEL LIPIDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS AXOLABS GMBH (DE) 2015-02-19 US disclosed
US-20150030669-A1 TARGETING AMINOACID LIPIDS MERCK PATENT GMBH (DE) 2015-01-29 US disclosed
US-20140288154-A1 Lipid Formulated Compositions and Methods for Inhibiting Expression of Eg5 And VEGF Genes ALNYLAM PHARMACEUTICALS, INC. (US) 2014-09-25 US disclosed
US-20140170175-A1 NOVEL LIPIDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS AXOLABS GMBH (DE) 2014-06-19 US disclosed
EP-2496238-A1 LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF TRANSTHYRETIN (TTR) Alnylam Pharmaceuticals, Inc. (US) 2012-09-12 EP disclosed
WO-2011056883-A1 LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF TRANSTHYRETIN (TTR) ALNYLAM PHARMACEUTICALS, INC. (US) 2011-05-12 WO disclosed
US-20100267806-A1 LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 AND VEGF GENES ALNYLAM PHARMACEUTICALS, INC. 2010-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150050295-A9 NOVEL LIPIDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS PHOSPHO1, NPC1L1, PLIN3 DNM1 408/4885MEN1 3635/4885KMT2A 4277/4885
US-20140288154-A1 Lipid Formulated Compositions and Methods for Inhibiting Expression of Eg5 And VEGF Genes KIF5A, KIF5C, KIF11 DNM1 561/4885MEN1 3122/4885KMT2A 1423/4885
US-20160076029-A1 siRNA Therapy for Transthyretin (TTR) Related Ocular Amyloidosis TTR, CRYAA, SARNP DNM1 2320/4885MEN1 4015/4885KMT2A 3632/4885
US-20140170175-A1 NOVEL LIPIDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS PHOSPHO1, NPC1L1, PLIN3 DNM1 408/4885MEN1 3635/4885KMT2A 4277/4885
US-11510988-B2 Targeting aminoacid lipids PTDSS2, DNPEP, FABP1 DNM1 3145/4885MEN1 3628/4885KMT2A 1677/4885
US-20150030669-A1 TARGETING AMINOACID LIPIDS PTDSS2, DNPEP, FABP1 DNM1 3145/4885MEN1 3628/4885KMT2A 1677/4885
US-20100267806-A1 LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 AND VEGF GENES KIF5A, KIF5C, KIF11 DNM1 561/4885MEN1 3122/4885KMT2A 1423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.