Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.38 |
| ▸ | LPL | P06858 | 4/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18171890 | 0.80 | DGAT1 (0.34) | DGAT1LIPGLPLHTT | |
| SCHEMBL18171863 | 0.79 | LPL (0.37) | DGAT1LIPGLPLIRAK4SNCA | |
| SCHEMBL29414473 | 0.77 | LPL (0.38) | DGAT1LIPGLPLPIK3CAIRAK4 | |
| SCHEMBL1818313 | 0.77 | LPL (0.38) | DGAT1LIPGLPLPIK3CAIRAK4 | |
| SCHEMBL18171886 | 0.76 | PDGFRB (0.54) | DGAT1SMN1; SMN2KMT2ALIPGLPL | |
| SCHEMBL18171876 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTTSHRKMT2AERAP1 | |
| SCHEMBL780459 | 0.76 | MAOB (0.49) | SMN1; SMN2MAPTTSHRKMT2AERAP1 | |
| SCHEMBL31503579 | 0.75 | TLR9 (0.52) | DGAT1SMN1; SMN2MAPTLIPGLPL | |
| SCHEMBL28597119 | 0.74 | LPL (0.38) | LIPGLPLIRAK4SNCAEGFR | |
| SCHEMBL5801456 | 0.73 | LIPG (0.54) | DGAT1TSHRLIPGLPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016170163-A1 | SUBSTITUTED QUINOXALINES AND BENZOTRIAZINE P70S6 KINASE INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |