Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.39 |
| ▸ | LPL | P06858 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1530858 | 0.87 | PDGFRB (0.47) | PDGFRBPDGFRAMEN1KMT2ACLK4 | |
| SCHEMBL18171891 | 0.81 | EGFR (0.40) | PDGFRBPDGFRADGAT1LIPGLPL | |
| SCHEMBL15550766 | 0.80 | DGAT1 (0.53) | PDGFRBPDGFRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31240616 | 0.80 | DGAT1 (0.53) | PDGFRBPDGFRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL18171882 | 0.79 | NUDT1 (0.40) | LIPGLPLMAP4K4 | |
| SCHEMBL12070285 | 0.78 | NOS2 (0.56) | KDM4EALDH1A1HPGDDGAT1NOS2 | |
| SCHEMBL30472985 | 0.76 | EGFR (0.40) | PDGFRBPDGFRADGAT1LIPGLPL | |
| SCHEMBL18171877 | 0.76 | DGAT1 (0.43) | SMN1; SMN2DGAT1LMNALIPGLPL | |
| SCHEMBL31503579 | 0.76 | TLR9 (0.52) | PDGFRBALDH1A1SMN1; SMN2DGAT1LIPG | |
| SCHEMBL28490184 | 0.75 | RAB9A (0.55) | SMN1; SMN2LMNALIPGLPLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016170163-A1 | SUBSTITUTED QUINOXALINES AND BENZOTRIAZINE P70S6 KINASE INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |