Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.30 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18173844 | 0.84 | HSD17B10 (0.35) | HSD17B10ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18171984 | 0.80 | ALDH1A1 (0.45) | HSD17B10ALDH1A1SMN1; SMN2MEN1HPGD | |
| SCHEMBL1548680 | 0.72 | COPS5 (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL18173855 | 0.71 | KDM4E (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL18173837 | 0.71 | HSD17B10 (0.36) | HSD17B10ALDH1A1GRIA4NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28483071 | 0.70 | HSD17B10 (0.35) | HSD17B10ALDH1A1GRIA4NPC1RAB9A | |
| SCHEMBL560676 | 0.69 | PTGER1 (0.38) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9748006 | 0.68 | KDM4E (0.42) | HSD17B10ALDH1A1GRIA4NPC1RAB9A | |
| SCHEMBL3394882 | 0.68 | HCAR3 (0.33) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL30440870 | 0.68 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2HPGDCOPS5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531704-B | Pesticidally active polycyclic derivatives with sulfur-substituted five-membered ring heterocycles | 先正达参股股份有限公司 | 2021-01-01 | — | — | CN | disclosed |
| CN-108040481-B | Pesticidally active polycyclic derivatives with sulfur-substituted five-membered ring heterocycles | 先正达参股股份有限公司 | 2020-10-30 | — | — | CN | disclosed |
| EP-3656770-A2 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYCLES | Syngenta Participations AG (CH) | 2020-05-27 | — | — | EP | disclosed |
| EP-3656770-A2 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYCLES | Syngenta Participations AG (CH) | 2020-05-27 | — | — | EP | disclosed |
| EP-3286186-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-06 | — | — | EP | disclosed |
| EP-3286186-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-06 | — | — | EP | disclosed |
| EP-3286187-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-18 | — | — | EP | disclosed |
| EP-3286187-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-18 | — | — | EP | disclosed |
| US-10125139-B2 | Pesticidally active polycyclic derivatives with sulfur substituted five-membered ring heterocycles | SYNGENTA CROP PROTECTION AG (CH) | 2018-11-13 | — | — | US | disclosed |
| US-10104893-B2 | Pesticidally active polycyclic derivatives with sulfur substituted five membered ring heterocyles | SYNGENTA PARTICIPATIONS AG (CH) | 2018-10-23 | — | — | US | disclosed |
| US-20180099970-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-12 | — | — | US | disclosed |
| US-20180099970-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-12 | — | — | US | disclosed |
| US-20180099970-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-12 | — | — | US | disclosed |
| EP-3286186-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | Syngenta Participations AG (CH) | 2018-02-28 | — | — | EP | disclosed |
| EP-3286187-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | Syngenta Participations AG (CH) | 2018-02-28 | — | — | EP | disclosed |
| CN-107531704-A | Five-membered ring heterocycle with sulphur substitution kills harmful organism activity Polycyclic derivative | 先正达参股股份有限公司 | 2018-01-02 | — | — | CN | disclosed |
| WO-2016169886-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA CROP PROTECTION AG (CH) | 2016-10-27 | — | — | WO | disclosed |
| WO-2016169882-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-27 | — | — | WO | disclosed |
| WO-2016169882-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-27 | — | — | WO | disclosed |
| WO-2016169886-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA CROP PROTECTION AG (CH) | 2016-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099970-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | DDT, NIT2, SQOR | HSD17B10 2192/4885ALDH1A1 1590/4885GRIA4 2829/4885 |
| US-10104893-B2 | Pesticidally active polycyclic derivatives with sulfur substituted five membered ring heterocyles | SQOR, DDT, QSOX1 | HSD17B10 2324/4885ALDH1A1 1226/4885GRIA4 3057/4885 |
| US-10125139-B2 | Pesticidally active polycyclic derivatives with sulfur substituted five-membered ring heterocycles | DDT, SQOR, NIT2 | HSD17B10 2751/4885ALDH1A1 1357/4885GRIA4 2440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.