Methacrylic Acid

Methacrylic Acid

SCHEMBL1817343

C=C(C)C(=O)O.CC(O)N1CCCC1=O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA3 P07451 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA5A P35218 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA13 Q8N1Q1 1/20 0.45
CA14 Q9ULX7 1/20 0.45
CA5B Q9Y2D0 1/20 0.45
CHRM2 P08172 2/20 0.38
CHRM4 P08173 2/20 0.38
CHRM5 P08912 2/20 0.38
CHRM1 P11229 2/20 0.38
CHRM3 P20309 2/20 0.38
PIK3CD O00329 1/20 0.36
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL29881172 0.90 LMNA (0.50) LMNACA12CA1CA2CA3
SCHEMBL39044 0.86
SCHEMBL27689543 0.86
SCHEMBL1817230 0.84 ALDH1A1 (0.44) LMNACA12CA1CA2CA3
Acrylic Acid SCHEMBL21798556 0.83 LMNA (0.45) LMNACA12CA1CA2CA3
Urea SCHEMBL14776158 0.82 LMNA (0.59) LMNACA12CA1CA2CA3
SCHEMBL7198087 0.80 LMNA (0.46) LMNACA12CA1CA2CA3
SCHEMBL8558383 0.78 LMNA (0.44) LMNACA12CA1CA2CA3
Methylpyrrolidone SCHEMBL5063791 0.77 BRD4 (0.63) LMNACA12CA1CA2CA3
SCHEMBL4154528 0.75 LMNA (0.44) LMNACA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers ISP INVESTMENTS LLC (US) 2024-02-27 US claimed
EP-3884963-A1 NAPROXEN/DEXAMETHASONE-BASED NANOPARTICLES Consejo Superior de Investigaciones Científicas (CSIC) (ES) 2021-09-29 EP claimed
EP-3377546-B1 PROCESS FOR THE PREPARATION OF HYDROXYETHYLPYRROLIDONE METHACRYLATE/GLYCIDYL METHACRYLATE COPOLYMERS ISP INVESTMENTS LLC (US) 2020-10-21 EP claimed
US-10274852-B2 Coating compositions for forming toner coatings ISP INVESTMENTS LLC (US) 2019-04-30 US claimed
US-20180346627-A1 HYDROXYETHYLPYRROLIDONE METHACRYLATE/GLYCIDYL METHACRYLATE COPOLYMERS ISP INVESTMENTS LLC (US) 2018-12-06 US claimed
US-20180346628-A1 POLYMERS FOR ORAL CARE COMPOSITIONS ISP INVESTMENTS LLC (US) 2018-12-06 US claimed
US-20180327628-A1 COATING COMPOSITIONS FOR FORMING TONER COATINGS ISP INVESTMENTS LLC (US) 2018-11-15 US claimed
WO-2018106666-A1 ORAL CARE COPOLYMERS AND COMPOSITIONS AND METHODS FOR USE ISP INVESTMENTS LLC (US) 2018-06-14 WO claimed
US-9821589-B2 Coating compositions for forming toner receptive coatings ISP INVESTMENTS LLC (US) 2017-11-21 US claimed
US-20160282737-A1 COATING COMPOSITIONS FOR FORMING TONER COATINGS ISP INVESTMENTS INC. (US) 2016-09-29 US claimed
US-20160059607-A1 COATING COMPOSITIONS FOR FORMING TONER RECEPTIVE COATINGS ISP INVESTMENTS INC. (US) 2016-03-03 US claimed
US-20160053131-A1 COATING COMPOSITIONS FOR FORMING TONER COATINGS ISP INVESTMENTS INC. (US) 2016-02-25 US claimed
WO-2014160604-A1 COATING COMPOSITIONS FOR FORMING TONER COATINGS ISP INVESTMENTS INC. (US) 2014-10-02 WO claimed
WO-2014160631-A1 COATING COMPOSITIONS FOR FORMING TONER COATINGS ISP INVESTMENTS INC. (US) 2014-10-02 WO claimed
WO-2014160672-A1 COATING COMPOSITIONS FOR FORMING TONER RECEPTIVE COATINGS ISP INVESTMENTS INC. (US) 2014-10-02 WO claimed
EP-3377549-B1 PROLIFEROUS POLYMERS COMPRISING LACTAMIC MOIETIES ISP INVESTMENTS LLC (US) 2024-09-04 EP disclosed
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers ISP INVESTMENTS LLC (US) 2024-02-27 US disclosed
WO-2011063208-A1 ALKYL LACTAM ESTER POLYMERS, AND USES THEREOF ISP INVESTMENTS INC. (US) 2011-05-26 WO disclosed
US-7750100-B2 Catalytic process for preparing (meth)acrylates from N-hydroxyalkylated lactams BASF AKTIENGESELLSCHAFT (DE) 2010-07-06 US disclosed
US-20070123673-A1 CATALYTIC PROCESS FOR PREPARING (METH)ACRYLATES FROM N-HYDROXYALKYLATED LACTAMS BASF AKTIENGESELLSCHAFT (DE) 2007-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180346628-A1 POLYMERS FOR ORAL CARE COMPOSITIONS MPO, SMARCC1, PTMA LMNA 1614/4885CA12 3205/4885CA1 1877/4885
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers MMAB, PCNA, HMBS LMNA 2499/4885CA12 1204/4885CA1 867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.