Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.61 |
| ▸ | HPGD | P15428 | 11/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | USP2 | O75604 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180849 | 0.79 | ALDH1A1 (0.66) | PKMALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL12632684 | 0.78 | ALDH1A1 (0.68) | PKMALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL14825171 | 0.77 | PKM (0.63) | PKMPOLBALDH1A1HPGDKDM4E | |
| SCHEMBL26296197 | 0.74 | CYP1A2 (0.71) | PKMALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL18177318 | 0.73 | ALDH1A1 (0.84) | PKMALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL14305225 | 0.72 | ALDH1A1 (0.63) | PKMPOLBALDH1A1HPGDKDM4E | |
| SCHEMBL10036547 | 0.70 | ALDH1A1 (1.00) | PKMPOLBALDH1A1HPGDKDM4E | |
| SCHEMBL29725974 | 0.69 | CNR2 (0.60) | PKMALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL34468119 | 0.68 | TSHR (0.66) | PKMPOLBALDH1A1HPGDNPC1 | |
| SCHEMBL17817446 | 0.68 | CYP1A2 (0.61) | PKMPOLBALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | NUTECH VENTURES | 2016-10-27 | — | — | US | disclosed |
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | NUTECH VENTURES | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | UGDH, G6PD, DPYD | PKM 1024/4885POLB 1599/4885ALDH1A1 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.