Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.66 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 8/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.47 |
| ▸ | CASP7 | P55210 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18177318 | 0.85 | ALDH1A1 (0.84) | ALDH1A1MAPTPKMHPGDRAB9A | |
| SCHEMBL12632684 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MAPTPKMHPGDRAB9A | |
| SCHEMBL18177319 | 0.79 | PKM (1.00) | ALDH1A1MAPTPKMHPGDRAB9A | |
| SCHEMBL14825171 | 0.75 | PKM (0.63) | ALDH1A1MAPTPKMHPGDRAB9A | |
| SCHEMBL14305225 | 0.74 | ALDH1A1 (0.63) | ALDH1A1MAPTPKMHPGDRAB9A | |
| SCHEMBL26296197 | 0.74 | CYP1A2 (0.71) | ALDH1A1MAPTPKMHPGDRAB9A | |
| SCHEMBL7002469 | 0.71 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| SCHEMBL7007163 | 0.71 | MAPT (0.65) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| SCHEMBL4140802 | 0.71 | KMT2A (0.56) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| SCHEMBL8288650 | 0.70 | ALDH1A1 (0.68) | ALDH1A1MAPTHPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | NUTECH VENTURES | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | UGDH, G6PD, DPYD | ALDH1A1 54/4885MAPT 2722/4885PKM 1024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.