Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18154212 | 0.88 | HSD11B1 (0.46) | HSD11B1L3MBTL1ALDH1A1MAPK1CCR5 | |
| SCHEMBL19836971 | 0.87 | HSD11B1 (0.47) | HSD11B1JAK2JAK1MEN1KMT2A | |
| SCHEMBL6687688 | 0.84 | L3MBTL1 (0.43) | HSD11B1L3MBTL1ALDH1A1MAPK1CCR5 | |
| SCHEMBL18154101 | 0.83 | KLK7 (0.42) | HSD11B1L3MBTL1ALDH1A1MAPK1CCR5 | |
| SCHEMBL8893633 | 0.83 | L3MBTL1 (0.45) | HSD11B1L3MBTL1ALDH1A1MAPK1CCR5 | |
| SCHEMBL18163696 | 0.83 | CCR5 (0.47) | HSD11B1L3MBTL1CCR5SIGMAR1 | |
| SCHEMBL18154352 | 0.82 | HSD11B1 (0.48) | HSD11B1CCR5JAK2JAK1MEN1 | |
| SCHEMBL5727402 | 0.81 | CCR5 (0.41) | HSD11B1L3MBTL1CCR5CHRM3 | |
| SCHEMBL18154489 | 0.81 | L3MBTL1 (0.41) | HSD11B1L3MBTL1ALDH1A1MAPK1CCR5 | |
| SCHEMBL6681828 | 0.81 | ENPP2 (0.43) | HSD11B1L3MBTL1ALDH1A1MAPK1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265448-A1 | RILUZOLE PRODRUGS AND THEIR USE | Biohaven Pharmaceutical Holding Company Ltd. (US) | 2018-01-10 | — | — | EP | disclosed |
| WO-2016140879-A9 | RILUZOLE PRODRUGS AND THEIR USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-11-03 | — | — | WO | disclosed |