SCHEMBL18154101

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18154489	0.89	L3MBTL1 (0.41)	KLK7KLK5L3MBTL1ALDH1A1MAPK1
	SCHEMBL6687688	0.87	L3MBTL1 (0.43)	L3MBTL1ALDH1A1MAPK1HSD11B1CCR5
	SCHEMBL8893633	0.86	L3MBTL1 (0.45)	L3MBTL1ALDH1A1MAPK1HSD11B1CCR5
	SCHEMBL6681828	0.84	ENPP2 (0.43)	L3MBTL1ALDH1A1MAPK1HSD11B1CCR5
	SCHEMBL18154212	0.84	HSD11B1 (0.46)	KLK7KLK5L3MBTL1ALDH1A1MAPK1
	SCHEMBL5727402	0.84	CCR5 (0.41)	L3MBTL1HSD11B1CCR5
	SCHEMBL29440195	0.83	KLK7 (0.40)	KLK7KLK5L3MBTL1ALDH1A1MAPK1
	SCHEMBL18163696	0.83	CCR5 (0.47)	L3MBTL1HSD11B1CCR5
	SCHEMBL18190877	0.83	HSD11B1 (0.41)	KLK7KLK5L3MBTL1ALDH1A1MAPK1
	SCHEMBL19836971	0.83	HSD11B1 (0.47)	HSD11B1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.