Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 11/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 11/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 3/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16564739 | 0.90 | RORC (0.39) | NOD2NOD1PPARDPPARAGAA | |
| SCHEMBL16564738 | 0.77 | MTNR1A (0.53) | MTNR1A | |
| SCHEMBL18197243 | 0.74 | GAA (0.43) | GAAMTNR1ARORC | |
| SCHEMBL18013076 | 0.73 | RORC (0.61) | RORC | |
| SCHEMBL18197140 | 0.73 | RORC (0.61) | RORC | |
| Ethoxycarbonyl Group SCHEMBL29291835 | 0.66 | AR (0.46) | ARMTNR1A | |
| SCHEMBL30738393 | 0.65 | AR (0.52) | ARMTNR1A | |
| SCHEMBL11627496 | 0.65 | MTNR1A (0.57) | MTNR1A | |
| SCHEMBL8652335 | 0.64 | MTNR1A (0.41) | GAAMTNR1A | |
| SCHEMBL6754202 | 0.63 | AR (0.38) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663469-B2 | RORγ modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160318870-A1 | RORy MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318870-A1 | RORy MODULATORS | RORB, RORC, RORA | NOD2 857/4885NOD1 991/4885PPARD 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.