Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 3/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ULK1 | O75385 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16564686 | 0.86 | GAA (0.46) | GAAIGF1RRORC | |
| SCHEMBL431492 | 0.77 | TRPV1 (0.41) | IGF1RKMT2A | |
| SCHEMBL30358011 | 0.76 | IGF1R (0.46) | IGF1RLMNAALDH1A1TP53CYP1A2 | |
| SCHEMBL18197189 | 0.74 | NOD2 (0.35) | GAARORCMTNR1A | |
| SCHEMBL30358050 | 0.74 | IGF1R (0.46) | IGF1RALDH1A1TP53CYP1A2HPGD | |
| SCHEMBL3893061 | 0.74 | IGF1R (0.46) | IGF1RALDH1A1TP53CYP1A2HPGD | |
| SCHEMBL30357998 | 0.74 | IGF1R (0.46) | IGF1RALDH1A1TP53CYP1A2HPGD | |
| SCHEMBL7335768 | 0.74 | ALDH1A1 (0.51) | IGF1RALDH1A1TP53CYP1A2HPGD | |
| SCHEMBL30358032 | 0.74 | ALDH1A1 (0.51) | IGF1RALDH1A1TP53CYP1A2HPGD | |
| SCHEMBL926907 | 0.70 | SMYD3 (0.56) | GAAIGF1RALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663469-B2 | RORγ modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160318870-A1 | RORy MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318870-A1 | RORy MODULATORS | RORB, RORC, RORA | GAA 2554/4885IGF1R 2843/4885LMNA 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.