Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20340486 | 0.90 | ALDH1A1 (0.37) | ALDH1A1SIGMAR1EPHX2TP53SMN1; SMN2 | |
| SCHEMBL20340485 | 0.78 | RAB9A (0.42) | SMN1; SMN2HPGDCYP3A4CYP2C19RAB9A | |
| SCHEMBL20340487 | 0.78 | RAB9A (0.36) | ALDH1A1TP53SMN1; SMN2HPGDCYP3A4 | |
| SCHEMBL774870 | 0.73 | RAB9A (0.42) | ALDH1A1SMN1; SMN2HPGDCYP3A4CYP2C19 | |
| SCHEMBL776366 | 0.73 | HPGD (0.39) | ALDH1A1TP53SMN1; SMN2HPGDCYP3A4 | |
| SCHEMBL18199502 | 0.69 | RAB9A (0.41) | ALDH1A1TP53SMN1; SMN2HPGDCYP3A4 | |
| SCHEMBL5067337 | 0.69 | RAB9A (0.49) | SMN1; SMN2HPGDCYP3A4CYP2C19RAB9A | |
| SCHEMBL18199497 | 0.69 | RAB9A (0.49) | SMN1; SMN2HPGDCYP3A4CYP2C19RAB9A | |
| SCHEMBL16853213 | 0.69 | TRPV1 (0.40) | ALDH1A1SIGMAR1EPHX2EPHX1TAS1R3 | |
| SCHEMBL19538672 | 0.68 | PSEN1 (0.36) | ALDH1A1HPGDCYP3A4CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207363-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2024-06-27 | — | — | US | disclosed |
| US-10039809-B2 | Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2018-08-07 | — | — | US | disclosed |
| US-10010589-B2 | — | — | 2018-07-03 | — | — | US | disclosed |
| US-20160317623-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160317623-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | SGMS1, SGMS2, PHOSPHO1 | ALDH1A1 4240/4885SIGMAR1 4522/4885EPHX2 1256/4885 |
| US-10010589-B2 | — | TYMP, MTAP, TUBB6 | ALDH1A1 3205/4885SIGMAR1 3890/4885EPHX2 1459/4885 |
| US-20240207363-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | SGMS1, SGMS2, PHOSPHO1 | ALDH1A1 4240/4885SIGMAR1 4522/4885EPHX2 1256/4885 |
| US-10039809-B2 | Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof | SGMS1, SGMS2, PHOSPHO1 | ALDH1A1 4240/4885SIGMAR1 4522/4885EPHX2 1256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.