SCHEMBL1819964

SCHEMBL1819964

COc1nc[c]cc1C#N

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.37
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
GAA P10253 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
RECQL P46063 1/20 0.33
IMPDH2 P12268 1/20 0.32
IMPDH1 P20839 1/20 0.32
USP2 O75604 1/20 0.32
SQOR Q9Y6N5 1/20 0.30
POLB P06746 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9480869 0.81 GAA (0.39) KDM4EALDH1A1MEN1KMT2AGAA
SCHEMBL2067238 0.75
SCHEMBL4160153 0.74
SCHEMBL2264178 0.72 KMT2A (0.32) KMT2A
SCHEMBL5938473 0.72
SCHEMBL3459140 0.71
SCHEMBL750927 0.71
SCHEMBL2227478 0.71
SCHEMBL9100046 0.68
SCHEMBL5939966 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109071506-B Substituted 2- (hetero) arylimidazolyl carboxamides as pest control agents 拜耳作物科学股份公司 2021-03-02 CN claimed
US-10544124-B2 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-01-28 US claimed
US-20190047982-A1 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-02-14 US claimed
EP-3414236-A1 SUBSTITUIERTED 2-(HET)ARYL-IMIDAZOLYL-CARBOXYAMIDES AS PEST CONTROL AGENTS Bayer CropScience Aktiengesellschaft (DE) 2018-12-19 EP claimed
WO-2017137338-A1 SUBSTITUIERTED 2-(HET)ARYL-IMIDAZOLYL-CARBOXYAMIDES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-08-17 WO claimed
WO-2011057892-A1 2,3-DIHYDROBENZOXAZINE AND 2,3-DIHYDROBENZOTHIAZINE DERIVATES AS HIF-INHIBITORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASES ELARA PHARMACEUTICALS GMBH (DE) 2011-05-19 WO claimed
EP-4199911-A1 PHARMACEUTICAL FORMULATIONS COMPRISING A MALT1 INHIBITOR AND A MIXTURE OF POLYETHYLENE GLYCOL WITH A FATTY ACID JANSSEN Pharmaceutica NV (BE) 2023-06-28 EP disclosed
US-20220192185-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HIGHLY SULFONATED LIGNOSULFONATE BASF SE (DE) 2022-06-23 US disclosed
US-20220183278-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HYDROPHOBIC FUMED SILICA BASF SE (DE) 2022-06-16 US disclosed
US-20220159957-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN BASF SE (DE) 2022-05-26 US disclosed
EP-3962269-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN BASF SE (DE) 2022-03-09 EP disclosed
WO-2022037661-A1 PHARMACEUTICAL FORMULATIONS COMPRISING A MALT1 INHIBITOR AND A MIXTURE OF POLYETHYLENE GLYCOL WITH A FATTY ACID JANSSEN PHARMACEUTICA NV (BE) 2022-02-24 WO disclosed
CN-113795147-A Stabilization of suspension concentrates by ethoxylated glycerol triricinoleate 巴斯夫欧洲公司 2021-12-14 CN disclosed
WO-2017137338-A1 SUBSTITUIERTED 2-(HET)ARYL-IMIDAZOLYL-CARBOXYAMIDES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-08-17 WO disclosed
US-20140005163-A1 1H-IMIDAZO[4,5-C]QUINOLINONE DERIVATIVES NOVARTIS AG (CH) 2014-01-02 US disclosed
US-8476294-B2 1H-imidazo[4,5-c]quinolinone derivatives NOVARTIS AG (CH) 2013-07-02 US disclosed
EP-2438064-A1 1H-IMIDAZO[4,5-c]QUINOLINONE DERIVATIVES Novartis AG (CH) 2012-04-11 EP disclosed
WO-2011057892-A1 2,3-DIHYDROBENZOXAZINE AND 2,3-DIHYDROBENZOTHIAZINE DERIVATES AS HIF-INHIBITORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASES ELARA PHARMACEUTICALS GMBH (DE) 2011-05-19 WO disclosed
US-20100317657-A1 1H-IMIDAZO[4,5-c]QUINOLINONE DERIVATIVES NOVARTIS AG 2010-12-16 US disclosed
WO-2010139731-A1 1H-IMIDAZO[4,5-c]QUINOLINONE DERIVATIVES NOVARTIS AG (CH) 2010-12-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190047982-A1 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides DDT, CYP4X1, CYP4Z1 KDM4E 231/4885ALDH1A1 3432/4885MEN1 3925/4885
US-20220159957-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN ERO1A, ERLIN2, ERLIN1 KDM4E 3095/4885ALDH1A1 2619/4885MEN1 4500/4885
US-20220192185-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HIGHLY SULFONATED LIGNOSULFONATE LSS, STS, U2SURP KDM4E 2108/4885ALDH1A1 571/4885MEN1 2638/4885
US-20220183278-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HYDROPHOBIC FUMED SILICA RCC1, SAMM50, PIGS KDM4E 3555/4885ALDH1A1 2627/4885MEN1 632/4885
US-20100317657-A1 1H-IMIDAZO[4,5-c]QUINOLINONE DERIVATIVES PRKCA, CSNK1A1, ABL1 KDM4E 1280/4885ALDH1A1 2405/4885MEN1 3285/4885
US-20140005163-A1 1H-IMIDAZO[4,5-C]QUINOLINONE DERIVATIVES PRKCA, CSNK1A1, ABL1 KDM4E 1280/4885ALDH1A1 2405/4885MEN1 3285/4885
US-10544124-B2 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides DDT, CYP4X1, CYP4Z1 KDM4E 231/4885ALDH1A1 3432/4885MEN1 3925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.