SCHEMBL182014

SCHEMBL182014

C=C(C)C(=O)NC(CC)S(=O)(=O)O

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL310237 0.85 TGFBR1 (0.44) TGFBR1
SCHEMBL3660408 0.83 TGFBR1 (0.31) TGFBR1
SCHEMBL3662683 0.83 TGFBR1 (0.31) TGFBR1
SCHEMBL11690191 0.83 ALDH1A1 (0.43) TGFBR1
SCHEMBL1561700 0.81 TGFBR1 (0.44) TGFBR1
SCHEMBL5013368 0.81 TGFBR1 (0.49) TGFBR1
Potassium Ion SCHEMBL3656408 0.81 TGFBR1 (0.44) TGFBR1
O-Tolylamine SCHEMBL11690194 0.81 TDP1 (0.37) TGFBR1
SCHEMBL8539211 0.80 TSHR (0.34)
SCHEMBL3656406 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8361484-B2 Polymer systems for lung volume reduction therapy AERIS THERAPEUTICS, INC. (US) 2013-01-29 US claimed
US-20110244254-A1 Anticorrosion coatings with reactive polyelectrolyte complex system SONG ZHIQIANG 2011-10-06 US claimed
US-20100040538-A1 Polymer Systems for Lung Volume Reduction Therapy CANADIAN IMPERIAL BANK OF COMMERCE (CA) 2010-02-18 US claimed
EP-2059227-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY Aeris Therapeutics, Inc. (US) 2009-05-20 EP claimed
WO-2008039827-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY AERIS THERAPEUTICS, INC. (US) 2008-04-03 WO claimed
EP-1243564-B1 Process for preventing formation of scale KURITA WATER IND LTD (JP) 2007-08-15 EP claimed
EP-1201720-B1 Printing fluid additives promoting overcoat adhesion HEWLETT PACKARD CO (US) 2004-09-15 EP claimed
US-6656365-B2 Within water cooling/supply systems, via ozone which is used for disinfection, and high molecular weight homo/copolymers of acrylic acid, methacyrlic acid, maleic acid, maleic anhydride, and itaconic acid KURITA WATER INDUSTRIES LTD. (JP) 2003-12-02 US claimed
US-6177197-B1 INK RECEIVING LAYER IS A CROSSLINKED PRODUCT OF POLYVINYL ALCOHOL RESIN AND CARBODIIMIDE CROSSLINKING AGENT NIPPON INDUSTRIES, INC. (JP) 2001-01-23 US claimed
US-4319014-A UNDATURATED CARBOXYLIC ACID COPOLYMER WITH UNDATURATED SULFONATE COMONOMER MODIFIED BY A MERCAPTAN UNIROYAL, INC. (US) 1982-03-09 US claimed
JP-57057705-A None JP disclosed
JP-3093892-A None JP disclosed
US-12617181-B2 Multilayer structure, and packaging material for retort using same KURARAY CO., LTD. (JP) 2026-05-05 US disclosed
US-20260085184-A1 ADHESIVE RESIN COMPOSITION KURARAY CO., LTD. (JP) 2026-03-26 US disclosed
EP-4715042-A1 METHOD FOR PRODUCING CELLS Kuraray Co., Ltd. (JP) 2026-03-25 EP disclosed
EP-0003516-B1 AQUOUS DISPERSIONS OF COPOLYMERS WITH CARBONYL GROUPS THAT CONTAIN HYDRAZINE DERIVATIVES AND HEAVY METAL IONS BASF Aktiengesellschaft (DE) 1981-04-01 EP disclosed
EP-0025979-A1 Aqueous solution or dispersion of a styrene-maleic acid anhydride copolymer, process for its preparation and its use HOECHST AKTIENGESELLSCHAFT (DE) 1981-04-01 EP disclosed
US-4250070-A ALSO CONTAINING HEAVY METAL IONS; STORAGE STABILITY; CROSSLINKING; COATINGS BASF AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed
US-4008293-A ACRYLIC COPOLYMER, AMINOPLAST, BINDER PPG INDUSTRIES, INC. (US) 1977-02-15 US disclosed
JP-S05757705-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617181-B2 Multilayer structure, and packaging material for retort using same VMA21, PUF60, RBM39 TGFBR1 2252/4885
US-20100040538-A1 Polymer Systems for Lung Volume Reduction Therapy GFER, MUC1, CTH TGFBR1 700/4885
US-20260085184-A1 ADHESIVE RESIN COMPOSITION COL1A1, ICAM1, COL2A1 TGFBR1 1656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.